MeiraGTx Holdings plc - Ordinary Shares, $0.00003881 par value per share (MGTX) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2018 to Q4 2025

Type / Class
Equity / Ordinary Shares, $0.00003881 par value per share
Symbol
MGTX on Nasdaq
Shares outstanding
80,294,700
Price per share
$8.00
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
65,158,422
Total reported value
$518,005,559
% of total 13F portfolios
0%
Share change
+961,598
Value change
+$7,552,773
Number of holders
128
Price from insider filings
$8.00
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of MeiraGTx Holdings plc - Ordinary Shares, $0.00003881 par value per share (MGTX) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
PERCEPTIVE ADVISORS LLC 13% $85,934,055 10,441,562 Perceptive Advisors LLC 31 Dec 2025
Rubric Capital Management LP 7.9% $45,573,943 6,175,331 Rubric Capital Management LP 31 Dec 2025
Adage Capital Management, L.P. 5.2% $34,439,077 4,184,578 Adage Capital Management, L.P. 30 Sep 2025
Prosight Management, LP 4% -28% $23,702,995 -$8,448,499 3,211,788 -26% W. Lawrence Hawkins 31 Dec 2025

As of 31 Dec 2025, 128 institutional investors reported holding 65,158,422 shares of MeiraGTx Holdings plc - Ordinary Shares, $0.00003881 par value per share (MGTX). This represents 81% of the company’s total 80,294,700 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of MeiraGTx Holdings plc - Ordinary Shares, $0.00003881 par value per share (MGTX) together control 76% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Sanofi 15% 12,197,737 0% 31% $96,972,009
PERCEPTIVE ADVISORS LLC 13% 10,326,103 -18% 1.5% $82,092,519
JOHNSON & JOHNSON 8.3% 6,641,064 0% 9.5% $52,796,459
Rubric Capital Management LP 7.7% 6,175,331 +66% 0.59% $49,093,881
ADAGE CAPITAL PARTNERS GP, L.L.C. 5% 4,000,000 -4.4% 0.05% $31,800,000
Prosight Management, LP 4% 3,209,788 -22% 5.3% $25,517,815
MILLENNIUM MANAGEMENT LLC 4% 3,176,390 +24% 0.02% $25,252,300
BlackRock, Inc. 3.8% 3,069,844 +11% 0% $24,405,260
683 Capital Management, LLC 3.2% 2,559,082 -2.5% 1.7% $20,344,701
MORGAN STANLEY 2.3% 1,829,252 +47% 0% $14,542,554
Knoll Capital Management, LLC 1.6% 1,250,000 0% 4.6% $9,937,500
Erste Asset Management GmbH 0.98% 789,702 +11% 0.05% $6,275,375
STATE STREET CORP 0.91% 729,445 +7.1% 0% $5,799,088
22NW, LP 0.73% 586,519 0% 3.6% $4,662,826
GEODE CAPITAL MANAGEMENT, LLC 0.71% 573,783 +3.3% 0% $4,561,574
Long Focus Capital Management, LLC 0.65% 524,745 0% 0.21% $4,171,723
VANGUARD GROUP INC 0.62% 494,753 +6.6% 0% $3,933,287
GOLDMAN SACHS GROUP INC 0.57% 456,744 +76% 0% $3,631,115
Opaleye Management Inc. 0.49% 390,844 0.41% $3,107,210
D. E. Shaw & Co., Inc. 0.48% 381,763 +120% 0% $3,035,016
J. Goldman & Co LP 0.4% 319,687 -82% 0.1% $2,541,512
Hennion & Walsh Asset Management, Inc. 0.38% 308,509 +183% 0.08% $2,452,647
Woodline Partners LP 0.37% 300,323 +50% 0.01% $2,387,568
Jefferies Financial Group Inc. 0.37% 298,242 0.02% $2,371,024
STEMPOINT CAPITAL LP 0.36% 287,689 +251% 0.39% $2,287,128

Institutional Holders of MeiraGTx Holdings plc - Ordinary Shares, $0.00003881 par value per share (MGTX) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 65,158,422 $518,005,559 +$7,552,773 $7.95 128
2025 Q3 64,115,394 $527,564,099 +$100,848 $8.23 122
2025 Q2 64,273,449 $419,562,716 +$27,529,421 $6.52 111
2025 Q1 59,986,380 $406,655,139 +$13,171,914 $6.78 118
2024 Q4 58,134,853 $353,880,152 +$5,661,044 $6.09 101
2024 Q3 45,221,185 $188,552,401 +$19,157,134 $4.17 97
2024 Q2 40,458,048 $170,235,110 +$4,338,640 $4.21 91
2024 Q1 39,300,324 $238,469,096 +$641,712 $6.07 95
2023 Q4 39,193,056 $275,136,034 +$9,570,624 $7.02 86
2023 Q3 37,791,917 $185,560,138 +$956,121 $4.91 74
2023 Q2 37,549,331 $252,327,936 +$61,583,237 $6.72 77
2023 Q1 28,748,444 $148,619,405 -$5,267,767 $5.17 88
2022 Q4 29,625,998 $193,116,514 +$5,062,552 $6.52 98
2022 Q3 27,968,146 $234,567,872 -$9,091,785 $8.41 98
2022 Q2 28,548,680 $216,121,658 -$5,764,085 $7.57 105
2022 Q1 29,291,750 $405,685,931 +$11,811,095 $13.85 101
2021 Q4 28,368,763 $672,844,608 +$17,527,958 $23.74 95
2021 Q3 27,863,121 $367,263,288 -$1,783,285 $13.18 79
2021 Q2 27,969,634 $433,466,019 +$13,341,762 $15.50 76
2021 Q1 27,129,412 $384,781,966 +$5,393,087 $14.43 79
2020 Q4 26,738,368 $404,815,585 +$66,577,970 $15.14 90
2020 Q3 22,138,540 $293,123,916 +$16,367,005 $13.24 82
2020 Q2 20,907,650 $261,758,875 +$10,066,092 $12.52 78
2020 Q1 20,093,813 $270,060,598 +$42,993,852 $13.44 82
2019 Q4 16,682,969 $333,992,017 +$16,114,615 $20.02 85
2019 Q3 15,884,005 $253,345,768 +$49,225,801 $15.95 81
2019 Q2 12,692,608 $334,563,403 +$25,170,435 $26.88 68
2019 Q1 11,974,218 $205,287,171 +$83,916,121 $17.23 54
2018 Q4 7,221,365 $69,612,048 +$7,485,483 $9.64 37
2018 Q3 6,408,742 $87,153,000 -$155,481 $13.60 35
2018 Q2 6,512,433 $74,625,000 +$74,625,013 $11.46 23