| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 6.7% | $87,815,414 | 11,186,677 | The Vanguard Group | 31 Dec 2025 |
As of 31 Dec 2025, 223 institutional investors reported holding 100,827,262 shares of Xeris Biopharma Holdings, Inc. - Common Stock (XERS). This represents 61% of the company’s total 165,974,436 outstanding shares.
The largest institutional shareholders of Xeris Biopharma Holdings, Inc. - Common Stock (XERS) together control 45% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BlackRock, Inc. | 7.6% | 12,639,318 | +6% | 0% | $99,218,645 |
| VANGUARD GROUP INC | 6.7% | 11,186,677 | +14% | 0% | $87,815,416 |
| D. E. Shaw & Co., Inc. | 4.6% | 7,574,850 | +30% | 0.05% | $59,462,573 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.6% | 4,275,989 | +3.3% | 0% | $33,571,396 |
| STATE STREET CORP | 2.5% | 4,116,924 | +10% | 0% | $32,317,853 |
| Qube Research & Technologies Ltd | 2.1% | 3,498,197 | +6.8% | 0.04% | $27,460,846 |
| Driehaus Capital Management LLC | 1.8% | 2,980,567 | +14% | 0.16% | $23,397,451 |
| Nuveen, LLC | 1.7% | 2,806,806 | -0.75% | 0.01% | $22,033,428 |
| MORGAN STANLEY | 1.6% | 2,707,783 | -16% | 0% | $21,256,104 |
| WELLINGTON MANAGEMENT GROUP LLP | 1.4% | 2,286,598 | +294% | 0% | $17,949,794 |
| Rosalind Advisors, Inc. | 1.3% | 2,111,700 | +18% | 6.4% | $16,576,845 |
| TWO SIGMA INVESTMENTS, LP | 1% | 1,732,667 | +7.3% | 0.02% | $13,601,436 |
| Parkman Healthcare Partners LLC | 1% | 1,691,585 | -5.6% | 1.3% | $13,278,942 |
| GOLDMAN SACHS GROUP INC | 0.94% | 1,568,421 | -13% | 0% | $12,312,105 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.85% | 1,403,824 | -3% | 0% | $11,020,018 |
| Legal & General Group Plc | 0.84% | 1,396,265 | +2.9% | 0% | $10,954,263 |
| CenterBook Partners LP | 0.84% | 1,391,590 | +99% | 0.53% | $10,923,982 |
| NORTHERN TRUST CORP | 0.84% | 1,386,829 | +1.7% | 0% | $10,886,607 |
| Granahan Investment Management, LLC | 0.74% | 1,223,404 | +249% | 0.41% | $9,603,721 |
| KENNEDY CAPITAL MANAGEMENT LLC | 0.73% | 1,213,969 | +0.2% | 0.2% | $9,529,657 |
| Connor, Clark & Lunn Investment Management Ltd. | 0.64% | 1,058,692 | -38% | 0.02% | $8,310,732 |
| ACADIAN ASSET MANAGEMENT LLC | 0.59% | 971,598 | +5.5% | 0.01% | $7,622,000 |
| Knott David M Jr | 0.58% | 970,000 | -4.4% | 3.5% | $7,614,500 |
| AQR CAPITAL MANAGEMENT LLC | 0.58% | 957,579 | -2.6% | 0% | $7,516,995 |
| DEUTSCHE BANK AG\ | 0.57% | 940,592 | -40% | 0% | $7,383,647 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 100,827,262 | $791,486,867 | +$25,419,628 | $7.85 | 223 |
| 2025 Q3 | 96,902,264 | $788,823,196 | +$58,407,958 | $8.14 | 229 |
| 2025 Q2 | 90,495,534 | $422,617,978 | +$16,622,096 | $4.67 | 200 |
| 2025 Q1 | 86,799,982 | $476,523,606 | +$123,713,876 | $5.49 | 199 |
| 2024 Q4 | 65,548,446 | $222,208,577 | +$5,693,687 | $3.39 | 161 |
| 2024 Q3 | 63,918,467 | $182,169,401 | +$11,712,690 | $2.85 | 143 |
| 2024 Q2 | 60,623,914 | $136,403,872 | +$57,516 | $2.25 | 132 |
| 2024 Q1 | 60,495,199 | $133,691,334 | +$1,259,202 | $2.21 | 140 |
| 2023 Q4 | 59,921,867 | $140,817,138 | +$3,980,290 | $2.35 | 118 |
| 2023 Q3 | 55,319,172 | $102,889,496 | -$2,383,422 | $1.86 | 109 |
| 2023 Q2 | 55,920,487 | $146,506,955 | +$17,809,976 | $2.62 | 101 |
| 2023 Q1 | 49,463,144 | $80,622,599 | -$5,927,964 | $1.63 | 89 |
| 2022 Q4 | 53,916,182 | $71,703,555 | -$5,395,029 | $1.33 | 93 |
| 2022 Q3 | 57,306,752 | $89,403,802 | -$3,332,109 | $1.56 | 97 |
| 2022 Q2 | 59,291,260 | $91,305,115 | +$12,225,836 | $1.54 | 95 |
| 2022 Q1 | 50,404,861 | $129,034,768 | +$23,839,809 | $2.56 | 97 |
| 2021 Q4 | 40,971,724 | $120,062,000 | +$117,961,261 | $2.93 | 85 |
| 2021 Q3 | 704,170 | $1,725,000 | +$1,725,000 | $2.45 | 1 |