| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 16% | -9.4% | $116,977,477 | -$11,261,518 | 11,130,112 | -8.8% | BlackRock, Inc. | 31 Mar 2025 |
| PRIMECAP MANAGEMENT CO/CA/ | 15% | $98,219,914 | 10,527,322 | PRIMECAP MANAGEMENT CO/CA/ | 30 Jun 2025 | |||
| VANGUARD GROUP INC | 10% | +0.8% | $105,464,036 | +$967,756 | 7,169,547 | +0.93% | The Vanguard Group | 28 Nov 2025 |
| BIOTECHNOLOGY VALUE FUND L P | 10% | +50% | $109,217,253 | +$38,495,142 | 7,133,720 | +54% | BVF PARTNERS L P/IL | 31 Dec 2025 |
| RTW INVESTMENTS, LP | 8.7% | $72,972,963 | 6,221,054 | RTW Investments, LP | 30 Sep 2025 | |||
| EcoR1 Capital, LLC | 6.4% | $71,038,400 | 4,640,000 | EcoR1 Capital, LLC | 31 Dec 2025 | |||
| STATE STREET CORP | 6.3% | +22% | $69,006,059 | +$12,608,382 | 4,507,254 | +22% | STATE STREET CORPORATION | 31 Dec 2025 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2.4% | $19,862,315 | 1,693,292 | T. Rowe Price Associates, Inc. | 30 Sep 2025 |
As of 31 Dec 2025, 202 institutional investors reported holding 81,803,177 shares of Xencor Inc - Common Stock (XNCR). This represents 113% of the company’s total 72,500,000 outstanding shares.
The largest institutional shareholders of Xencor Inc - Common Stock (XNCR) together control 97% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BlackRock, Inc. | 16% | 11,927,218 | +1% | 0% | $182,605,708 |
| PRIMECAP MANAGEMENT CO/CA/ | 14% | 10,218,322 | -4.3% | 0.12% | $156,442,509 |
| VANGUARD GROUP INC | 9.9% | 7,165,450 | +0.87% | 0% | $109,703,040 |
| BVF INC/IL | 9.8% | 7,133,720 | +160% | 3.7% | $109,217,253 |
| RTW INVESTMENTS, LP | 9.3% | 6,777,461 | +8.9% | 1% | $103,762,928 |
| STATE STREET CORP | 6.2% | 4,507,254 | +23% | 0% | $69,006,059 |
| EcoR1 Capital, LLC | 4.5% | 3,251,112 | -47% | 2.3% | $49,774,525 |
| TCG Crossover Management, LLC | 3.4% | 2,452,138 | 0% | 1.2% | $37,542,233 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.4% | 1,752,918 | +1.4% | 0% | $26,842,201 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2.2% | 1,601,762 | -5.4% | 0% | $24,524,000 |
| MORGAN STANLEY | 2.1% | 1,508,727 | +67% | 0% | $23,098,626 |
| Defilade Capital Management, L.P. | 2% | 1,414,755 | 0% | 2.9% | $21,659,899 |
| Legal & General Group Plc | 1.8% | 1,308,088 | +2.8% | 0% | $20,026,828 |
| DIMENSIONAL FUND ADVISORS LP | 1.7% | 1,249,288 | -21% | 0% | $19,125,117 |
| BAKER BROS. ADVISORS LP | 1.5% | 1,102,106 | 0% | 0.1% | $16,873,243 |
| GOLDMAN SACHS GROUP INC | 1% | 753,258 | -26% | 0% | $11,532,380 |
| JOHNSON & JOHNSON | 1% | 748,062 | 0% | 2.1% | $11,452,829 |
| Jefferies Financial Group Inc. | 0.99% | 720,440 | +620% | 0.09% | $11,029,936 |
| Lynx1 Capital Management LP | 0.97% | 705,558 | 2.2% | $10,802,093 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.97% | 700,435 | +1.8% | 0% | $10,723,660 |
| NORTHERN TRUST CORP | 0.93% | 674,657 | -5.3% | 0% | $10,328,998 |
| UBS Group AG | 0.88% | 638,021 | -46% | 0% | $9,768,101 |
| BANK OF AMERICA CORP /DE/ | 0.87% | 629,408 | -17% | 0% | $9,636,237 |
| MILLENNIUM MANAGEMENT LLC | 0.82% | 594,435 | -15% | 0.01% | $9,100,800 |
| PANAGORA ASSET MANAGEMENT INC | 0.81% | 583,778 | -6% | 0.03% | $8,937,641 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 81,803,177 | $1,252,175,462 | -$15,447,043 | $15.31 | 202 |
| 2025 Q3 | 81,931,427 | $960,178,354 | +$6,100,544 | $11.73 | 204 |
| 2025 Q2 | 82,284,537 | $646,977,988 | +$20,020,454 | $7.86 | 191 |
| 2025 Q1 | 78,656,178 | $836,867,995 | +$36,707,472 | $10.64 | 197 |
| 2024 Q4 | 74,962,874 | $1,722,861,698 | +$74,554,042 | $22.98 | 191 |
| 2024 Q3 | 72,099,278 | $1,450,233,173 | +$173,590,110 | $20.11 | 209 |
| 2024 Q2 | 63,677,276 | $1,205,414,340 | -$28,620,202 | $18.93 | 197 |
| 2024 Q1 | 64,955,561 | $1,437,354,893 | +$38,858,883 | $22.13 | 200 |
| 2023 Q4 | 63,438,288 | $1,346,794,541 | +$2,946,816 | $21.23 | 194 |
| 2023 Q3 | 63,240,815 | $1,274,307,664 | +$10,877,356 | $20.15 | 175 |
| 2023 Q2 | 62,681,983 | $1,566,006,651 | -$23,444,287 | $24.97 | 180 |
| 2023 Q1 | 63,583,668 | $1,771,628,071 | +$59,782,147 | $27.89 | 183 |
| 2022 Q4 | 61,547,949 | $1,602,582,831 | +$19,403,618 | $26.04 | 193 |
| 2022 Q3 | 60,849,265 | $1,581,417,958 | -$74,640,726 | $25.98 | 174 |
| 2022 Q2 | 59,843,119 | $1,638,192,397 | +$20,569,513 | $27.37 | 168 |
| 2022 Q1 | 59,286,835 | $1,582,158,680 | -$1,530,095 | $26.68 | 169 |
| 2021 Q4 | 59,174,089 | $2,372,958,496 | +$30,709,697 | $40.12 | 171 |
| 2021 Q3 | 58,120,007 | $1,898,467,165 | +$947,702 | $32.66 | 165 |
| 2021 Q2 | 58,041,765 | $2,001,234,431 | -$24,285,884 | $34.49 | 173 |
| 2021 Q1 | 58,525,232 | $2,519,282,177 | -$25,684,890 | $43.06 | 167 |
| 2020 Q4 | 59,098,973 | $2,579,349,505 | +$122,069 | $43.63 | 169 |
| 2020 Q3 | 59,168,606 | $2,295,311,877 | +$21,234,216 | $38.79 | 157 |
| 2020 Q2 | 58,636,892 | $1,899,277,122 | +$203,952,745 | $32.39 | 151 |
| 2020 Q1 | 52,380,712 | $1,565,845,143 | -$41,704,286 | $29.88 | 137 |
| 2019 Q4 | 53,521,828 | $1,840,592,912 | -$9,705,040 | $34.39 | 162 |
| 2019 Q3 | 53,716,146 | $1,811,934,409 | +$147,436,205 | $33.73 | 150 |
| 2019 Q2 | 48,892,888 | $2,001,111,237 | +$50,462,146 | $40.93 | 118 |
| 2019 Q1 | 48,039,063 | $1,492,133,555 | +$4,125,992 | $31.06 | 115 |
| 2018 Q4 | 47,831,492 | $1,729,047,723 | +$32,118,652 | $36.16 | 115 |
| 2018 Q3 | 46,792,493 | $1,822,675,621 | +$3,293,406 | $38.97 | 124 |
| 2018 Q2 | 46,774,405 | $1,731,076,239 | +$86,469,155 | $37.01 | 122 |
| 2018 Q1 | 44,718,509 | $1,340,651,579 | +$224,063,089 | $29.98 | 122 |
| 2017 Q4 | 37,369,817 | $819,172,426 | +$3,577,339 | $21.92 | 104 |
| 2017 Q3 | 37,140,169 | $851,162,220 | +$9,732,952 | $22.92 | 104 |
| 2017 Q2 | 36,836,630 | $777,612,692 | +$23,377,905 | $21.11 | 114 |
| 2017 Q1 | 35,650,517 | $852,741,478 | +$81,080,319 | $23.92 | 125 |
| 2016 Q4 | 35,035,653 | $922,088,537 | +$142,823,588 | $26.32 | 136 |
| 2016 Q3 | 29,626,637 | $724,863,086 | +$38,489,120 | $24.49 | 120 |
| 2016 Q2 | 28,213,616 | $535,759,236 | +$3,771,990 | $18.99 | 99 |
| 2016 Q1 | 28,006,868 | $375,809,000 | +$24,280,734 | $13.42 | 91 |
| 2015 Q4 | 26,171,247 | $382,476,117 | -$27,011,932 | $14.62 | 93 |
| 2015 Q3 | 28,373,464 | $347,020,935 | +$34,279,194 | $12.23 | 93 |
| 2015 Q2 | 25,251,465 | $554,774,155 | +$49,843,256 | $21.97 | 97 |
| 2015 Q1 | 23,319,707 | $357,257,260 | +$137,738,740 | $15.32 | 94 |
| 2014 Q4 | 14,119,842 | $225,905,985 | +$7,473,629 | $16.04 | 63 |
| 2014 Q3 | 13,435,605 | $124,719,599 | +$5,776,557 | $9.31 | 50 |
| 2014 Q2 | 12,796,476 | $148,692,713 | -$25,746,421 | $11.62 | 51 |
| 2014 Q1 | 15,007,873 | $176,041,000 | +$18,181,068 | $11.73 | 43 |