Werewolf Therapeutics, Inc. - Common Stock (HOWL) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2021 to Q4 2025

Type / Class
Equity / Common Stock
Symbol
HOWL on Nasdaq
Shares outstanding
47,916,629
Price per share
$0.71
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
14,735,208
Total reported value
$9,335,513
% of total 13F portfolios
0%
Share change
-1,994,785
Value change
-$2,241,745
Number of holders
49
Price from insider filings
$0.71
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Werewolf Therapeutics, Inc. - Common Stock (HOWL) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
RA CAPITAL MANAGEMENT, L.P. 14% -8% $13,162,175 -$129,035 6,681,307 -0.97% RA Capital Management, L.P. 04 Nov 2025
MPM BioVentures 2014, L.P. 6.9% -16% $2,136,074 -$386,130 3,368,670 -15% ANSBERT GADICKE 14 Jan 2026
Longwood Fund III, L.P. 3.5% $955,937 1,677,082 Longwood Fund III GP, LLC 31 Dec 2025
PFM Health Sciences, LP 0.9% -80% $437,210 -$2,729,747 401,110 -86% PFM Health Sciences, LP 30 Jun 2025

As of 31 Dec 2025, 49 institutional investors reported holding 14,735,208 shares of Werewolf Therapeutics, Inc. - Common Stock (HOWL). This represents 31% of the company’s total 47,916,629 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Werewolf Therapeutics, Inc. - Common Stock (HOWL) together control 30% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
RA CAPITAL MANAGEMENT, L.P. 14% 6,681,307 0% 0.04% $4,232,608
VANGUARD GROUP INC 2.9% 1,408,047 0% 0% $892,702
MPM BIOIMPACT LLC 2.9% 1,393,557 -42% 0.1% $883,515
BANK OF AMERICA CORP /DE/ 1.5% 737,550 -60% 0% $466,869
RENAISSANCE TECHNOLOGIES LLC 1.4% 677,766 +49% 0% $429,365
Lynx1 Capital Management LP 1.4% 655,926 0.08% $415,529
SPHERA FUNDS MANAGEMENT LTD. 1.3% 626,810 0% 0.08% $397,084
DC Funds, LP 1.2% 589,102 0% 26% $373,196
GEODE CAPITAL MANAGEMENT, LLC 0.7% 335,886 +1.5% 0% $212,838
MILLENNIUM MANAGEMENT LLC 0.5% 240,109 -24% 0% $152,109
Alyeska Investment Group, L.P. 0.49% 235,705 0% 0% $149,319
JANE STREET GROUP, LLC 0.33% 157,322 -41% 0% $99,663
STATE STREET CORP 0.25% 119,168 0% 0% $75,493
BlackRock, Inc. 0.21% 101,643 +0.32% 0% $64,391
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.21% 99,829 +7.3% 0% $63,242
NORTHERN TRUST CORP 0.18% 86,851 +32% 0% $55,020
BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.16% 77,000 -25% 0% $48,780
UBS Group AG 0.13% 60,708 +375% 0% $38,428
Vontobel Holding Ltd. 0.13% 60,003 +67% 0% $38,012
Regal Investment Advisors LLC 0.11% 52,593 +93% 0% $33,318
EDGEWOOD MANAGEMENT LLC 0.1% 50,000 0% 0% $31,675
MORGAN STANLEY 0.1% 46,002 +139% 0% $29,142
GOLDMAN SACHS GROUP INC 0.07% 34,073 -44% 0% $21,585
SIMPLEX TRADING, LLC 0.05% 24,054 +54% 0% $15,250
CERTUITY, LLC 0.03% 15,000 0% 0% $9,503

Institutional Holders of Werewolf Therapeutics, Inc. - Common Stock (HOWL) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 14,735,208 $9,335,513 -$2,241,745 $0.63 49
2025 Q3 21,108,242 $41,572,612 -$2,126,394 $1.97 62
2025 Q2 22,335,758 $24,343,246 -$5,335,449 $1.09 65
2025 Q1 27,445,533 $26,679,025 -$940,155 $0.97 70
2024 Q4 28,177,146 $41,701,476 -$7,785,512 $1.48 71
2024 Q3 32,205,548 $68,274,106 -$1,018,677 $2.12 68
2024 Q2 32,469,409 $79,220,415 -$5,272,473 $2.44 70
2024 Q1 32,251,087 $208,968,732 +$29,830,206 $6.48 59
2023 Q4 27,669,999 $106,805,060 +$14,923,168 $3.86 41
2023 Q3 23,882,934 $51,107,776 -$364,729 $2.14 34
2023 Q2 24,045,139 $73,334,928 +$110,396 $3.05 36
2023 Q1 24,035,818 $62,491,910 +$8,454,617 $2.60 37
2022 Q4 20,890,957 $42,845,289 -$4,124,677 $2.05 37
2022 Q3 20,956,559 $94,490,128 +$8,517,407 $4.51 39
2022 Q2 19,071,418 $78,002,023 +$194,911 $4.09 39
2022 Q1 18,982,797 $83,522,100 -$5,015,169 $4.40 47
2021 Q4 19,103,784 $227,525,761 -$818,751 $11.91 50
2021 Q3 18,418,726 $316,117,290 -$12,884,754 $17.16 41
2021 Q2 19,169,179 $334,041,360 +$334,041,360 $17.44 44