Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2018 to Q4 2025

Type / Class
Equity / Common stock, $0.00001 par value per share
Symbol
TWST on Nasdaq
Shares outstanding
61,113,534
Price per share
$42.94
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
74,979,703
Total reported value
$2,378,558,100
% of total 13F portfolios
0%
Share change
+942,387
Value change
+$34,756,239
Number of holders
237
Price from insider filings
$42.94
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
ARK Investment Management LLC 12% +15% $239,787,181 +$37,344,876 7,559,495 +18% ARK Investment Management LLC 31 Dec 2025
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 9.7% +55% $204,475,092 +$73,747,279 5,954,429 +56% WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 31 Dec 2025
Artisan Partners Limited Partnership 9.5% -10% $184,934,103 -$18,419,645 5,830,205 -9.1% Artisan Partners Asset Management Inc. 31 Dec 2025
EdgePoint Investment Group Inc. 8.8% +29% $184,680,211 +$44,493,376 5,377,991 +32% EdgePoint Investment Group Inc. 31 Dec 2025
BlackRock, Inc. 8.3% $197,947,718 4,927,750 BlackRock, Inc. 31 Mar 2025
STATE STREET CORP 5.1% +20% $86,926,233 +$15,338,157 3,089,063 +21% STATE STREET CORPORATION 30 Sep 2025
Invesco Ltd. 3.9% $91,850,982 2,347,929 Invesco Ltd. 30 Jun 2025

As of 31 Dec 2025, 237 institutional investors reported holding 74,979,703 shares of Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST). This represents 123% of the company’s total 61,113,534 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST) together control 102% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
ARK Investment Management LLC 12% 7,559,495 +12% 1.6% $239,787,194
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 9.7% 5,954,429 +44% 0.53% $188,874,488
BlackRock, Inc. 9.6% 5,894,972 -4.6% 0% $186,988,511
Artisan Partners Limited Partnership 9.5% 5,830,205 -9.1% 0.28% $184,934,095
VANGUARD GROUP INC 9.5% 5,776,198 +0.14% 0% $183,221,001
EdgePoint Investment Group Inc. 8.8% 5,377,991 +32% 1.4% $170,589,875
STATE STREET CORP 5.9% 3,627,818 +17% 0% $115,074,387
Amova Asset Management Americas, Inc. 3.1% 1,902,829 -10% 0.7% $60,262,594
Sumitomo Mitsui Trust Group, Inc. 3.1% 1,902,829 -10% 0.04% $60,357,736
Soleus Capital Management, L.P. 3% 1,861,802 -0.24% 2.5% $59,056,359
GOLDMAN SACHS GROUP INC 2.8% 1,696,594 +4.3% 0.01% $53,815,962
MILLENNIUM MANAGEMENT LLC 2.5% 1,497,746 -17% 0.03% $47,508,503
GEODE CAPITAL MANAGEMENT, LLC 2.4% 1,459,274 +0.75% 0% $46,296,523
Thrivent Financial for Lutherans 2.2% 1,361,355 -7% 0.08% $43,182,000
Invesco Ltd. 2.1% 1,290,271 -28% 0.01% $40,927,396
BAILLIE GIFFORD & CO 2.1% 1,276,195 +1.1% 0.03% $40,480,906
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 1.9% 1,173,100 +4.4% 0.01% $37,210,731
First Light Asset Management, LLC 1.9% 1,140,771 -4.5% 2.8% $36,185,256
MORGAN STANLEY 1.4% 866,356 -42% 0% $27,480,827
AMERICAN CENTURY COMPANIES INC 1.4% 865,634 +3.3% 0.01% $27,457,993
Tao Capital Management LP 1.4% 828,815 0% 23% $26,290,012
DIMENSIONAL FUND ADVISORS LP 1.3% 815,369 +3.1% 0.01% $25,864,898
WELLINGTON MANAGEMENT GROUP LLP 1.3% 813,122 +171% 0% $25,792,229
UBS Group AG 1.1% 662,317 +29% 0% $21,008,695
JENNISON ASSOCIATES LLC 1% 618,933 -2.5% 0.01% $19,632,554

Institutional Holders of Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 74,979,703 $2,378,558,100 +$34,756,239 $31.72 237
2025 Q3 73,764,582 $2,075,556,896 +$57,804,960 $28.14 235
2025 Q2 71,133,390 $2,616,814,853 +$58,445,660 $36.79 240
2025 Q1 69,532,083 $2,729,868,536 +$98,718,253 $39.26 260
2024 Q4 66,360,913 $3,083,489,168 +$6,148,856 $46.47 244
2024 Q3 66,073,350 $2,986,931,967 -$9,670,153 $45.18 240
2024 Q2 65,972,475 $3,251,056,592 +$28,344,193 $49.28 256
2024 Q1 67,075,830 $2,301,195,873 +$12,173,886 $34.31 230
2023 Q4 66,744,591 $2,459,763,309 +$20,095,641 $36.86 215
2023 Q3 66,341,769 $1,344,049,066 -$31,879,539 $20.26 191
2023 Q2 68,103,043 $1,393,371,812 +$106,475,508 $20.46 185
2023 Q1 63,810,827 $961,273,962 +$17,347,246 $15.08 197
2022 Q4 62,336,899 $1,484,114,188 +$31,639,333 $23.81 191
2022 Q3 59,850,512 $2,097,211,101 +$44,899,500 $35.24 206
2022 Q2 57,994,411 $2,008,438,723 -$90,076,201 $34.96 188
2022 Q1 54,121,106 $2,662,382,357 +$281,218,717 $49.38 193
2021 Q4 51,230,952 $3,958,124,330 +$152,934,374 $77.39 224
2021 Q3 48,658,857 $5,195,018,312 +$41,898,607 $106.97 229
2021 Q2 48,123,755 $6,401,051,212 +$152,118,907 $133.25 240
2021 Q1 46,988,226 $5,820,040,994 +$482,887,437 $123.86 234
2020 Q4 42,909,917 $6,062,828,297 +$547,775,260 $141.29 215
2020 Q3 39,702,868 $3,018,023,941 +$217,077,489 $75.97 191
2020 Q2 37,011,859 $1,675,114,837 +$285,296,567 $45.30 141
2020 Q1 30,828,177 $943,220,817 +$343,349,207 $30.58 116
2019 Q4 19,740,464 $414,547,368 +$39,243,468 $21.00 92
2019 Q3 15,673,899 $374,288,352 +$37,099,334 $23.88 82
2019 Q2 13,908,043 $401,736,443 +$231,712,763 $29.01 83
2019 Q1 6,003,624 $137,709,000 -$1,684,002 $23.18 47
2018 Q4 6,077,977 $137,438,000 +$137,438,002 $23.09 46