Tempus AI, Inc. - Class A Common Stock, $0.0001 Par Value Per Share (TEM) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2024 to Q4 2025

Type / Class
Equity / Class A Common Stock, $0.0001 Par Value Per Share
Symbol
TEM on Nasdaq
Shares outstanding
178,199,988
Price per share
$63.51
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
100,842,488
Total reported value
$5,956,167,914
% of total 13F portfolios
0.01%
Share change
+9,521,606
Value change
+$527,614,989
Number of holders
442
Price from insider filings
$63.51
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Tempus AI, Inc. - Class A Common Stock, $0.0001 Par Value Per Share (TEM) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
LEFKOFSKY ERIC P 24% -7.3% $2,923,620,275 -$143,612,055 42,767,997 -4.7% Eric Paul Lefkofsky 31 Dec 2025
BAILLIE GIFFORD & CO 5.8% -21% $782,276,913 -$209,726,388 9,692,441 -21% BAILLIE GIFFORD & CO 30 Sep 2025
VANGUARD GROUP INC 5.6% $762,032,101 9,441,607 The Vanguard Group 30 Sep 2025

As of 31 Dec 2025, 442 institutional investors reported holding 100,842,488 shares of Tempus AI, Inc. - Class A Common Stock, $0.0001 Par Value Per Share (TEM). This represents 57% of the company’s total 178,199,988 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Tempus AI, Inc. - Class A Common Stock, $0.0001 Par Value Per Share (TEM) together control 45% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
VANGUARD GROUP INC 5.8% 10,258,621 +8.7% 0.01% $605,771,570
BAILLIE GIFFORD & CO 4.9% 8,741,442 -9.8% 0.43% $516,182,150
ARK Investment Management LLC 4.2% 7,557,583 +5.3% 3% $446,275,249
BlackRock, Inc. 4.2% 7,516,110 +12% 0.01% $443,826,286
GC Wealth Management RIA, LLC 3.8% 6,761,507 15% $399,266,988
SOFTBANK GROUP CORP. 3% 5,405,406 0% 2.1% $319,189,224
JPMORGAN CHASE & CO 2.8% 4,909,920 -0.39% 0.02% $289,930,889
Sumitomo Mitsui Trust Group, Inc. 2% 3,504,823 +1.2% 0.12% $206,959,798
Amova Asset Management Americas, Inc. 2% 3,504,823 +1.2% 2.4% $206,959,798
MORGAN STANLEY 1.2% 2,083,394 -14% 0.01% $123,024,447
GEODE CAPITAL MANAGEMENT, LLC 1% 1,870,510 +8.2% 0.01% $110,478,320
FRANKLIN RESOURCES INC 1% 1,861,782 +28% 0.03% $109,938,228
STATE STREET CORP 0.91% 1,616,338 +9.8% 0% $95,444,759
TWO SIGMA INVESTMENTS, LP 0.89% 1,591,481 +29% 0.14% $93,976,953
VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.88% 1,573,530 -2.1% 0.33% $92,916,947
Alphabet Inc. 0.87% 1,551,102 0% 3.6% $91,592,573
UBS Group AG 0.83% 1,483,862 -32% 0.02% $87,622,052
D. E. Shaw & Co., Inc. 0.66% 1,180,315 -42% 0.05% $69,697,601
Lingotto Investment Management LLP 0.64% 1,143,526 +46% 1.2% $67,525,210
BANK OF AMERICA CORP /DE/ 0.64% 1,140,489 -53% 0% $67,345,875
CITADEL ADVISORS LLC 0.51% 902,570 +5044% 0.04% $53,296,759
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.48% 856,674 +124% 0.07% $50,586,600
NORGES BANK 0.46% 816,840 0.01% $48,234,402
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.42% 743,268 +4.7% 0.01% $43,889,975
MARSHALL WACE, LLP 0.41% 738,646 +1109% 0.04% $43,617,046

Institutional Holders of Tempus AI, Inc. - Class A Common Stock, $0.0001 Par Value Per Share (TEM) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 100,842,488 $5,956,167,914 +$527,614,989 $59.05 442
2025 Q3 92,454,668 $7,463,974,765 +$723,696,066 $80.71 436
2025 Q2 82,459,145 $5,239,711,439 +$1,531,466,643 $63.54 364
2025 Q1 59,102,332 $2,851,251,078 +$465,431,040 $48.24 283
2024 Q4 51,697,053 $1,745,594,200 +$299,216,180 $33.76 152
2024 Q3 38,502,961 $2,173,850,858 +$162,858,748 $56.60 96
2024 Q2 37,173,865 $1,301,063,362 +$1,301,063,362 $35.00 80