Tenaya Therapeutics, Inc. - Common Stock, par value $0.0001 per share (TNYA) Institutional Ownership

13F Institutional Holders and Ownership History from Q3 2021 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.0001 per share
Symbol
TNYA on Nasdaq
Shares outstanding
213,832,909
Price per share
$0.71
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
68,500,158
Total reported value
$48,733,471
% of total 13F portfolios
0%
Share change
+26,549,663
Value change
+$17,032,706
Number of holders
96
Price from insider filings
$0.71
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Tenaya Therapeutics, Inc. - Common Stock, par value $0.0001 per share (TNYA) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Woodline Partners LP 5% -26% $6,120,000 +$2,097,006 9,000,000 +52% Woodline Partners LP 30 Jun 2025
Empery Asset Management, LP 5% -50% $5,641,468 -$293,106 8,296,276 -4.9% Empery Asset Management, LP 30 Jun 2025
Casdin Capital, LLC 4.3% $3,231,826 6,732,971 Casdin Capital, LLC 04 Mar 2025
BlackRock, Inc. 1.7% -71% $1,670,287 -$1,566,919 2,732,800 -48% BlackRock, Inc. 30 Jun 2025
JPMORGAN CHASE & CO 2.8% -53% $1,096,279 -$1,378,097 2,283,914 -56% JPMORGAN CHASE & CO. 28 Feb 2025

As of 31 Dec 2025, 96 institutional investors reported holding 68,500,158 shares of Tenaya Therapeutics, Inc. - Common Stock, par value $0.0001 per share (TNYA). This represents 32% of the company’s total 213,832,909 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Tenaya Therapeutics, Inc. - Common Stock, par value $0.0001 per share (TNYA) together control 30% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Column Group LLC 4.4% 9,400,290 0% 8.1% $6,693,006
VANGUARD GROUP INC 4% 8,560,108 +69% 0% $6,094,797
Empery Asset Management, LP 2.5% 5,414,101 0% 3.4% $3,852,133
MILLENNIUM MANAGEMENT LLC 2.2% 4,615,746 +2.5% 0% $3,284,103
CITADEL ADVISORS LLC 2% 4,200,000 0% $2,988,300
Anson Funds Management LP 1.9% 4,152,966 0.41% $2,954,835
Alyeska Investment Group, L.P. 1.9% 4,000,000 0.01% $2,846,000
BlackRock, Inc. 1.8% 3,948,586 +70% 0% $2,809,419
BURKEHILL GLOBAL MANAGEMENT, LP 0.94% 2,000,000 0.09% $1,423,000
Kalehua Capital Management LLC 0.94% 2,000,000 0% 1.4% $1,423,000
RENAISSANCE TECHNOLOGIES LLC 0.87% 1,850,867 +10% 0% $1,316,892
ADAR1 Capital Management, LLC 0.7% 1,505,300 0.08% $1,071,021
SPHERA FUNDS MANAGEMENT LTD. 0.7% 1,500,000 0.22% $1,067,250
GSA CAPITAL PARTNERS LLP 0.69% 1,478,612 +220% 0.09% $1,052,000
MARSHALL WACE, LLP 0.66% 1,406,035 +8034% 0% $998,285
TWO SIGMA INVESTMENTS, LP 0.59% 1,266,075 +39% 0% $900,812
GEODE CAPITAL MANAGEMENT, LLC 0.56% 1,193,355 +1.5% 0% $849,415
Euclidean Capital LLC 0.47% 1,015,705 0% 0.2% $722,674
Alphabet Inc. 0.43% 915,705 0% 0.03% $650,151
Raiffeisen Bank International AG 0.42% 900,000 +157% 0.01% $630,000
JANE STREET GROUP, LLC 0.32% 678,460 +334% 0% $482,724
Mirador Capital Partners LP 0.27% 582,524 +2379% 0.06% $414,466
UBS Group AG 0.27% 579,601 +195% 0% $412,676
StepStone Group LP 0.22% 462,163 0% 0.19% $328,136
STATE STREET CORP 0.21% 445,821 0% 0% $317,202

Institutional Holders of Tenaya Therapeutics, Inc. - Common Stock, par value $0.0001 per share (TNYA) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 68,500,158 $48,733,471 +$17,032,706 $0.71 96
2025 Q3 34,529,364 $55,547,747 +$5,329,371 $1.62 89
2025 Q2 31,571,002 $19,291,816 -$9,941,570 $0.61 87
2025 Q1 48,166,604 $27,453,207 +$1,982,469 $0.57 104
2024 Q4 43,606,618 $62,359,118 -$25,849,595 $1.43 83
2024 Q3 57,630,896 $111,228,656 +$67,017 $1.93 91
2024 Q2 57,076,933 $176,981,415 +$2,253,617 $3.10 94
2024 Q1 56,023,483 $292,935,438 +$51,188,426 $5.23 89
2023 Q4 46,629,309 $151,075,893 -$9,232,276 $3.24 73
2023 Q3 49,741,215 $126,838,955 -$3,313,935 $2.55 77
2023 Q2 47,651,950 $279,717,125 +$15,890,634 $5.87 79
2023 Q1 45,028,141 $128,326,772 -$2,290,501 $2.85 65
2022 Q4 47,128,809 $94,724,321 +$22,977,493 $2.01 67
2022 Q3 35,221,703 $102,151,001 -$12,249,474 $2.90 67
2022 Q2 37,062,342 $208,638,443 -$1,855,716 $5.63 47
2022 Q1 37,349,150 $439,920,087 +$23,331,598 $11.78 50
2021 Q4 35,354,543 $667,600,957 +$18,069,398 $18.95 46
2021 Q3 24,450,664 $499,284,447 +$499,284,447 $20.65 44