| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| TCG Crossover GP II, LLC | 10% | +62% | $158,881,608 | +$58,581,305 | 13,521,839 | +58% | TCG Crossover GP II, L.P. | 31 Dec 2025 |
| FARALLON PARTNERS L L C/CA | 10% | $119,266,365 | 13,461,215 | Dapice Joshua J. | 31 Dec 2025 | |||
| Farallon Capital Partners, L.P. | 9.7% | +16% | $90,358,800 | +$13,440,000 | 10,757,000 | +17% | Dapice Joshua J. | 30 Sep 2025 |
| Adage Capital Management, L.P. | 7.9% | +281% | $124,643,107 | +$95,138,857 | 10,607,924 | +322% | Adage Capital Management, L.P. | 31 Dec 2025 |
| Woodline Partners LP | 7.5% | +32% | $118,348,644 | +$47,497,248 | 10,072,225 | +67% | Woodline Partners LP | 31 Dec 2025 |
| BlackRock, Inc. | 6.3% | +26% | $75,107,682 | +$26,758,396 | 8,477,165 | +55% | BlackRock, Inc. | 31 Dec 2025 |
| Invus Global Management, LLC | 6.1% | +16% | $95,943,144 | +$26,815,686 | 8,165,374 | +39% | Raymond Debbane | 31 Dec 2025 |
| VANGUARD GROUP INC | 5% | $59,813,656 | 6,750,977 | The Vanguard Group | 31 Dec 2025 | |||
| Third Rock Ventures IV, L.P. | 4.7% | -18% | $74,901,244 | -$17,625,000 | 6,374,574 | -19% | Third Rock Ventures IV, L.P. | 06 Feb 2026 |
| FMR LLC | 0% | $19,552 | 13,392 | FMR LLC | 29 Nov 2024 |
As of 31 Dec 2025, 168 institutional investors reported holding 172,391,306 shares of Tango Therapeutics, Inc. - Common Stock (TNGX). This represents 127% of the company’s total 135,353,744 outstanding shares.
The largest institutional shareholders of Tango Therapeutics, Inc. - Common Stock (TNGX) together control 109% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FARALLON CAPITAL MANAGEMENT LLC | 9.6% | 13,061,411 | +21% | 0.67% | $115,724,101 |
| TCG Crossover Management, LLC | 9.4% | 12,762,094 | +50% | 3.7% | $113,072,153 |
| Boxer Capital Management, LLC | 8% | 10,876,219 | +11% | 21% | $96,363,300 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 7.8% | 10,607,924 | +322% | 0.14% | $93,986,207 |
| Woodline Partners LP | 7.4% | 10,072,225 | +67% | 0.35% | $89,239,914 |
| BlackRock, Inc. | 6.3% | 8,540,797 | +51% | 0% | $75,671,463 |
| Siren, L.L.C. | 6% | 8,165,374 | +39% | 2.2% | $72,345,214 |
| TRV GP IV, LLC | 5.8% | 7,874,574 | -43% | 27% | $69,768,726 |
| Nextech Invest, Ltd. | 5.4% | 7,266,081 | +31% | 6.2% | $64,377,478 |
| VANGUARD GROUP INC | 5% | 6,750,977 | +34% | 0% | $59,813,655 |
| STATE STREET CORP | 4.6% | 6,218,567 | +85% | 0% | $55,096,504 |
| Balyasny Asset Management L.P. | 3.9% | 5,278,580 | +52% | 0.09% | $46,768,219 |
| GOLDMAN SACHS GROUP INC | 3.7% | 4,942,414 | +227% | 0.01% | $43,789,788 |
| Logos Global Management LP | 3.1% | 4,200,000 | +342% | 2.5% | $37,212,000 |
| Bellevue Group AG | 2.9% | 3,927,670 | 0.66% | $34,799,156 | |
| Caligan Partners LP | 2.8% | 3,729,895 | 3% | $33,046,870 | |
| Nantahala Capital Management, LLC | 2.6% | 3,572,633 | +97% | 1.9% | $31,653,528 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 2.1% | 2,906,946 | 0.33% | $25,755,542 | |
| FMR LLC | 2.1% | 2,867,548 | +44524% | 0% | $25,406,475 |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 2% | 2,662,227 | 0.59% | $23,587,331 | |
| JANUS HENDERSON GROUP PLC | 2% | 2,644,237 | +15% | 0.01% | $23,467,604 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.9% | 2,553,656 | +36% | 0% | $22,629,824 |
| Deep Track Capital, LP | 1.8% | 2,454,562 | +69% | 0.5% | $21,747,419 |
| Vivo Capital, LLC | 1.6% | 2,154,780 | +177% | 1.2% | $19,091,351 |
| Point72 Asset Management, L.P. | 1.5% | 1,974,035 | -32% | 0.03% | $17,489,950 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 172,391,306 | $1,527,343,517 | +$294,774,478 | $8.86 | 168 |
| 2025 Q3 | 139,978,941 | $1,175,803,271 | +$109,407,056 | $8.40 | 141 |
| 2025 Q2 | 127,196,008 | $651,244,300 | +$113,427,538 | $5.12 | 114 |
| 2025 Q1 | 107,228,944 | $146,966,295 | -$1,500,604 | $1.37 | 119 |
| 2024 Q4 | 106,381,203 | $328,721,243 | -$120,601,739 | $3.09 | 134 |
| 2024 Q3 | 101,459,260 | $781,203,088 | -$3,564,439 | $7.70 | 119 |
| 2024 Q2 | 98,595,824 | $845,901,469 | +$2,628,498 | $8.58 | 116 |
| 2024 Q1 | 98,377,909 | $781,109,580 | +$30,778,538 | $7.94 | 124 |
| 2023 Q4 | 93,643,916 | $927,104,831 | +$41,143,001 | $9.90 | 118 |
| 2023 Q3 | 88,799,639 | $999,861,944 | +$236,872,193 | $11.26 | 99 |
| 2023 Q2 | 68,320,832 | $226,845,382 | -$7,737,842 | $3.32 | 89 |
| 2023 Q1 | 69,836,747 | $275,851,159 | +$1,770,332 | $3.95 | 91 |
| 2022 Q4 | 68,766,073 | $498,554,976 | +$12,927,727 | $7.25 | 83 |
| 2022 Q3 | 68,157,717 | $246,729,459 | -$12,119,590 | $3.62 | 86 |
| 2022 Q2 | 70,452,006 | $319,137,805 | -$11,072,751 | $4.53 | 76 |
| 2022 Q1 | 69,679,958 | $528,174,476 | +$13,385,662 | $7.58 | 70 |
| 2021 Q4 | 67,775,150 | $740,996,532 | +$24,899,642 | $10.94 | 57 |
| 2021 Q3 | 65,465,348 | $844,863,000 | +$844,863,000 | $12.93 | 45 |