Rezolute, Inc. - Common Stock, $0.001 par value per share (RZLT) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2020 to Q4 2025

Type / Class
Equity / Common Stock, $0.001 par value per share
Symbol
RZLT on Nasdaq
Shares outstanding
93,299,785
Price per share
$3.25
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
90,130,672
Total reported value
$212,706,921
% of total 13F portfolios
0%
Share change
+3,332,077
Value change
-$157,868,056
Number of holders
119
Price from insider filings
$3.25
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Rezolute, Inc. - Common Stock, $0.001 par value per share (RZLT) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
RA CAPITAL MANAGEMENT, L.P. 9.9% $146,288,898 15,302,186 RA Capital Healthcare Fund, L.P. 11 Dec 2025
BANK OF AMERICA CORP /DE/ 6.5% $14,372,832 6,064,486 BANK OF AMERICA CORP /DE/ 31 Dec 2025
Opaleye Management Inc. 5.3% $46,967,324 4,912,900 Opaleye Management Inc. 12 Dec 2025
BlackRock, Inc. 5.4% $45,886,185 4,881,509 BlackRock, Inc. 30 Sep 2025
VANGUARD GROUP INC 5.2% $11,295,619 4,788,511 The Vanguard Group 31 Dec 2025
Nantahala Capital Management, LLC 4.9% -41% $11,317,609 -$8,350,591 2,857,982 -42% Nantahala Capital Management, LLC 31 Dec 2024
FMR LLC 2.5% -83% $5,379,582 -$24,514,368 2,305,568 -82% FMR LLC 31 Dec 2025

As of 31 Dec 2025, 119 institutional investors reported holding 90,130,672 shares of Rezolute, Inc. - Common Stock, $0.001 par value per share (RZLT). This represents 97% of the company’s total 93,299,785 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Rezolute, Inc. - Common Stock, $0.001 par value per share (RZLT) together control 88% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
FEDERATED HERMES, INC. 18% 16,534,712 +18% 0.07% $39,021,920
RA CAPITAL MANAGEMENT, L.P. 9.8% 9,180,000 0.22% $21,664,800
BlackRock, Inc. 7.3% 6,768,206 +35% 0% $15,972,966
Opaleye Management Inc. 6.7% 6,287,156 +596% 2% $14,837,688
VANGUARD GROUP INC 5.1% 4,788,511 +8.6% 0% $11,300,886
Balyasny Asset Management L.P. 4.8% 4,506,861 +147% 0.02% $10,636,192
BANK OF AMERICA CORP /DE/ 4.6% 4,325,248 +237% 0% $10,207,585
STATE STREET CORP 4.3% 3,981,708 +90% 0% $9,396,831
UBS Group AG 3% 2,816,291 +4.5% 0% $6,646,447
Affinity Asset Advisors, LLC 2.5% 2,351,144 +12% 0.4% $5,548,700
FMR LLC 2.5% 2,305,568 -82% 0% $5,441,140
Integral Health Asset Management, LLC 2.1% 2,000,000 0% 0.24% $4,720,000
GEODE CAPITAL MANAGEMENT, LLC 2.1% 1,954,733 +5.8% 0% $4,614,157
BARCLAYS PLC 2% 1,911,066 +517% 0% $4,510,115
MILLENNIUM MANAGEMENT LLC 1.8% 1,711,194 +855% 0% $4,038,418
Vestal Point Capital, LP 1.8% 1,686,000 0.15% $3,978,960
MORGAN STANLEY 1.6% 1,516,435 +349% 0% $3,578,786
JANE STREET GROUP, LLC 1.5% 1,407,699 +1182% 0% $3,322,170
GOLDMAN SACHS GROUP INC 1.4% 1,304,782 +141% 0% $3,079,286
AMERIPRISE FINANCIAL INC 1.2% 1,093,925 +335% 0% $2,581,663
GREAT POINT PARTNERS LLC 1% 951,809 -61% 0.73% $2,246,269
22NW, LP 0.88% 820,653 0% 1.5% $1,936,741
Velan Capital Investment Management LP 0.8% 750,000 0% 1% $1,770,000
NORTHERN TRUST CORP 0.79% 737,315 -4.5% 0% $1,740,063
KENNEDY CAPITAL MANAGEMENT LLC 0.75% 697,855 +2292% 0.03% $1,646,938

Institutional Holders of Rezolute, Inc. - Common Stock, $0.001 par value per share (RZLT) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 90,130,672 $212,706,921 -$157,868,056 $2.36 119
2025 Q3 86,920,142 $817,052,884 +$108,361,490 $9.40 115
2025 Q2 77,913,169 $347,492,575 +$151,537,051 $4.46 91
2025 Q1 45,040,344 $130,615,009 -$811,015 $2.90 76
2024 Q4 43,207,187 $211,713,139 +$30,093,702 $4.90 71
2024 Q3 38,544,894 $186,942,117 -$3,938,820 $4.85 59
2024 Q2 39,525,913 $169,961,526 +$54,178,980 $4.30 51
2024 Q1 27,042,621 $68,962,251 +$246,860 $2.55 33
2023 Q4 28,952,301 $28,740,703 +$4,794,203 $0.99 31
2023 Q3 23,889,501 $31,534,322 -$458,985 $1.32 29
2023 Q2 24,223,878 $47,962,915 +$49,684 $1.98 28
2023 Q1 24,226,408 $46,514,454 -$475,670 $1.92 31
2022 Q4 24,450,852 $50,611,801 -$822,266 $2.07 34
2022 Q3 24,446,950 $67,002,000 -$497,915 $2.74 30
2022 Q2 24,538,369 $79,207,000 +$56,346,030 $3.23 33
2022 Q1 7,085,710 $23,951,000 -$2,289,045 $3.38 19
2021 Q4 7,529,707 $35,989,000 +$22,778,341 $4.78 21
2021 Q3 2,373,215 $17,647,000 +$1,206,770 $7.48 13
2021 Q2 2,211,492 $31,558,000 -$1,377,636 $14.27 11
2021 Q1 2,477,026 $17,487,000 -$208,256 $7.06 10
2020 Q4 2,506,346 $30,230,000 +$30,230,000 $11.99 7