Replimune Group, Inc. - Common Stock, par value $0.001 per share (REPL) Institutional Ownership

13F Institutional Holders and Ownership History from Q3 2018 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.001 per share
Symbol
REPL on Nasdaq
Shares outstanding
80,239,086
Price per share
$7.39
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
79,746,267
Total reported value
$775,188,444
% of total 13F portfolios
0%
Share change
-3,630,911
Value change
+$18,004,096
Number of holders
162
Price from insider filings
$7.39
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Replimune Group, Inc. - Common Stock, par value $0.001 per share (REPL) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
BAKER BROS. ADVISORS LP 14% $99,960,291 11,045,336 Baker Bros. Advisors LP 07 Mar 2025
PRICE T ROWE ASSOCIATES INC /MD/ 11% $34,805,312 8,306,757 T. Rowe Price Associates, Inc. 30 Sep 2025
RTW INVESTMENTS, LP 8.2% $26,798,117 6,395,732 RTW Investments, LP 30 Sep 2025
Point72 Asset Management, L.P. 4.7% -17% $15,209,289 -$3,488,586 3,629,902 -19% Point72 Asset Management, L.P. 30 Sep 2025
VANGUARD GROUP INC 4.8% $32,542,424 3,595,848 The Vanguard Group 31 Dec 2024
Forbion Capital Fund III Cooperatief U.A. 3.5% -43% $22,579,279 -$11,344,215 2,808,368 -33% Forbion Capital Fund III Cooperatief U.A. 31 Dec 2025
Redmile Group, LLC 0.7% -95% $2,245,077 -$18,279,751 535,818 -89% Redmile Group, LLC 30 Sep 2025

As of 31 Dec 2025, 162 institutional investors reported holding 79,746,267 shares of Replimune Group, Inc. - Common Stock, par value $0.001 per share (REPL). This represents 99% of the company’s total 80,239,086 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Replimune Group, Inc. - Common Stock, par value $0.001 per share (REPL) together control 85% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BAKER BROS. ADVISORS LP 14% 11,045,336 0% 0.63% $107,360,666
PRICE T ROWE ASSOCIATES INC /MD/ 10% 8,262,296 -0.53% 0.01% $80,310,000
RTW INVESTMENTS, LP 8.9% 7,140,352 +12% 0.7% $69,404,221
BlackRock, Inc. 7.6% 6,069,633 +5.1% 0% $58,996,834
VANGUARD GROUP INC 4.7% 3,776,198 +8.5% 0% $36,704,645
STATE STREET CORP 4.6% 3,693,107 +26% 0% $35,897,000
FMR LLC 3.7% 2,981,580 +119% 0% $28,980,955
FCPM III SERVICES B.V. 3.5% 2,808,368 -32% 3.6% $27,297,337
D. E. Shaw & Co., Inc. 3.2% 2,575,042 +538% 0.02% $25,029,408
TORONTO DOMINION BANK 2.8% 2,229,527 +62% 0.04% $21,671,002
Erste Asset Management GmbH 2.6% 2,120,000 +30% 0.17% $20,619,200
ADAGE CAPITAL PARTNERS GP, L.L.C. 2.3% 1,807,368 0.03% $17,567,617
GEODE CAPITAL MANAGEMENT, LLC 2.2% 1,750,194 +3.2% 0% $17,015,933
Commodore Capital LP 1.8% 1,425,000 0.92% $13,851,000
Rosalind Advisors, Inc. 1.8% 1,410,497 5.3% $13,710,031
ADAR1 Capital Management, LLC 1.5% 1,241,322 +27% 0.9% $12,065,650
DIMENSIONAL FUND ADVISORS LP 1.4% 1,119,357 -11% 0% $10,880,742
Redmile Group, LLC 1.4% 1,099,756 +105% 0.79% $10,689,628
JPMORGAN CHASE & CO 1.2% 925,173 +2334% 0% $8,992,681
MILLENNIUM MANAGEMENT LLC 1% 834,562 -48% 0.01% $8,111,943
MORGAN STANLEY 1% 814,888 -41% 0% $7,920,720
Boxer Capital Management, LLC 0.93% 750,000 -29% 1.6% $7,290,000
Jefferies Financial Group Inc. 0.89% 714,226 0.06% $6,942,277
GOLDMAN SACHS GROUP INC 0.82% 658,096 -42% 0% $6,396,693
Invesco Ltd. 0.76% 613,015 +297% 0% $5,958,506

Institutional Holders of Replimune Group, Inc. - Common Stock, par value $0.001 per share (REPL) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 79,746,267 $775,188,444 +$18,004,096 $9.72 162
2025 Q3 82,882,164 $347,530,533 -$49,961,720 $4.19 161
2025 Q2 80,960,067 $752,124,138 -$9,722,609 $9.29 173
2025 Q1 81,976,905 $799,308,276 +$36,933,791 $9.75 165
2024 Q4 77,881,821 $943,217,348 +$80,774,805 $12.11 155
2024 Q3 69,947,896 $766,692,674 -$7,687,757 $10.96 143
2024 Q2 70,902,356 $638,102,295 +$37,351,096 $9.00 148
2024 Q1 67,014,350 $547,213,173 +$8,620,113 $8.17 147
2023 Q4 66,033,045 $556,812,735 -$40,625,538 $8.43 138
2023 Q3 56,812,005 $970,921,194 +$32,501,979 $17.11 126
2023 Q2 54,593,396 $1,267,069,422 +$26,630,495 $23.22 139
2023 Q1 53,816,654 $948,994,808 +$90,895,078 $17.66 138
2022 Q4 48,204,772 $1,310,877,449 +$189,427,869 $27.20 135
2022 Q3 40,775,249 $704,191,848 -$8,659,480 $17.27 103
2022 Q2 39,999,317 $700,208,199 +$17,983,844 $17.48 98
2022 Q1 39,119,622 $665,006,692 -$35,451,893 $16.98 104
2021 Q4 38,825,604 $1,050,822,879 +$5,595,187 $27.10 97
2021 Q3 35,350,579 $1,048,056,990 +$5,527,419 $29.64 99
2021 Q2 34,863,218 $1,338,855,937 -$5,476,278 $38.42 109
2021 Q1 34,665,378 $1,057,669,955 +$1,013,258 $30.51 106
2020 Q4 34,484,345 $1,315,869,430 +$362,197,042 $38.15 112
2020 Q3 26,602,669 $611,849,920 +$25,676,805 $23.02 78
2020 Q2 25,420,897 $630,933,046 +$87,691,348 $24.85 75
2020 Q1 22,171,093 $220,779,588 -$470,574 $9.97 56
2019 Q4 22,018,833 $315,719,677 +$48,171,940 $14.35 61
2019 Q3 18,572,485 $257,907,605 -$14,772,415 $13.90 51
2019 Q2 19,565,712 $286,574,644 +$6,757,973 $14.66 53
2019 Q1 19,131,429 $291,385,593 +$17,749,806 $15.22 53
2018 Q4 18,156,099 $181,563,000 +$1,489,969 $10.00 50
2018 Q3 17,925,571 $288,599,000 +$288,599,000 $16.10 54