Rapport Therapeutics, Inc. - Common Stock, $0.001 par value per share (RAPP) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2024 to Q4 2025

Type / Class
Equity / Common Stock, $0.001 par value per share
Symbol
RAPP on Nasdaq
Shares outstanding
47,677,496
Price per share
$26.45
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
51,083,890
Total reported value
$1,549,883,454
% of total 13F portfolios
0%
Share change
+1,778,475
Value change
+$54,540,100
Number of holders
142
Price from insider filings
$26.45
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Rapport Therapeutics, Inc. - Common Stock, $0.001 par value per share (RAPP) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Third Rock Ventures V, L.P. 20% $81,198,952 7,135,233 Third Rock Ventures V, L.P. 31 Dec 2024
Cormorant Asset Management, LP 6.4% -5% $82,045,819 -$4,471,500 3,027,521 -5.2% Cormorant Asset Management, LP 31 Dec 2025
BlackRock, Inc. 5% $72,741,637 2,397,549 BlackRock, Inc. 31 Dec 2025
Sofinnova Venture Partners XI, L.P. 4.2% $29,155,258 1,947,579 Dr. James I. Healy ("Healy") 11 Sep 2025
JOHNSON & JOHNSON 4.9% $53,000,690 1,784,517 JOHNSON & JOHNSON 30 Sep 2025

As of 31 Dec 2025, 142 institutional investors reported holding 51,083,890 shares of Rapport Therapeutics, Inc. - Common Stock, $0.001 par value per share (RAPP). This represents 107% of the company’s total 47,677,496 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Rapport Therapeutics, Inc. - Common Stock, $0.001 par value per share (RAPP) together control 98% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
TRV GP V, LLC 15% 7,135,233 0% 50% $216,482,969
FMR LLC 15% 7,111,865 +2.8% 0.01% $215,773,984
ARCH Venture Management, LLC 7.8% 3,728,738 0% 17% $113,129,911
Capital International Investors 7.1% 3,402,529 0% 0.02% $103,232,730
Cormorant Asset Management, LP 6.4% 3,027,521 -5.2% 5.2% $91,854,987
GOLDMAN SACHS GROUP INC 6.3% 3,001,879 +24% 0.01% $91,077,009
BlackRock, Inc. 5.1% 2,431,862 +55% 0% $73,782,693
Sofinnova Investments, Inc. 4% 1,904,408 -2.2% 2.5% $57,779,739
VANGUARD GROUP INC 3.8% 1,817,757 +12% 0% $55,150,747
JOHNSON & JOHNSON 3.7% 1,784,517 0% 9.8% $54,142,246
BAKER BROS. ADVISORS LP 3.2% 1,547,090 0% 0.27% $46,938,711
Vestal Point Capital, LP 2.3% 1,110,000 +17% 1.2% $33,677,400
Polar Capital Holdings Plc 2.1% 1,004,728 +7% 0.14% $30,483,448
TRV GP VI, LLC 2% 969,218 0% 20% $29,406,074
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 2% 952,371 +6.7% 0.01% $28,894,936
PRICE T ROWE ASSOCIATES INC /MD/ 1.8% 881,609 -20% 0% $26,749,000
ALLIANCEBERNSTEIN L.P. 1.7% 788,411 -7.9% 0.01% $23,920,390
STATE STREET CORP 1.5% 714,821 +92% 0% $21,687,669
Siren, L.L.C. 1.5% 708,469 -33% 0.64% $21,494,949
GEODE CAPITAL MANAGEMENT, LLC 1.5% 694,734 +30% 0% $21,081,433
PERCEPTIVE ADVISORS LLC 1.4% 673,923 +67% 0.37% $20,446,824
T. Rowe Price Investment Management, Inc. 1.3% 619,029 -13% 0.01% $18,782,000
Invesco Ltd. 0.56% 267,120 +69% 0% $8,104,422
PRUDENTIAL FINANCIAL INC 0.53% 254,967 0.01% $7,735,699
BURKEHILL GLOBAL MANAGEMENT, LP 0.52% 250,000 0% 0.5% $7,585,000

Institutional Holders of Rapport Therapeutics, Inc. - Common Stock, $0.001 par value per share (RAPP) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 51,083,890 $1,549,883,454 +$54,540,100 $30.34 142
2025 Q3 49,276,697 $1,463,478,389 +$335,895,056 $29.70 123
2025 Q2 38,494,803 $437,875,302 +$4,896,059 $11.37 81
2025 Q1 38,102,588 $382,320,591 +$11,241,443 $10.03 77
2024 Q4 36,577,539 $648,890,836 -$29,671 $17.74 69
2024 Q3 28,444,042 $581,877,476 +$37,552,009 $20.48 55
2024 Q2 25,558,517 $593,435,106 +$593,435,106 $23.26 35