| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 10% | -9.1% | $29,564,292 | +$5,234,139 | 5,141,616 | +22% | JANUS HENDERSON GROUP PLC | 31 Dec 2025 |
| BlackRock, Inc. | 4.7% | -15% | $12,839,266 | +$1,412,386 | 2,408,868 | +12% | BlackRock, Inc. | 31 Dec 2025 |
| RA CAPITAL MANAGEMENT, L.P. | 4.9% | -50% | $5,974,448 | -$4,423,642 | 1,971,765 | -43% | RA Capital Management, L.P. | 30 Jun 2025 |
| Opaleye Management Inc. | 4.7% | -12% | $7,473,600 | -$410,400 | 1,730,000 | -5.2% | Opaleye Management, Inc. | 31 Mar 2025 |
| CITADEL ADVISORS LLC | 4.7% | $7,031,811 | 1,627,734 | Kenneth Griffin | 31 Dec 2024 | |||
| Woodline Partners LP | 3.9% | $5,751,035 | 1,331,258 | Woodline Partners LP | 31 Dec 2024 |
As of 31 Dec 2025, 103 institutional investors reported holding 39,817,794 shares of Protara Therapeutics, Inc. - Common Stock (TARA). This represents 77% of the company’s total 51,416,160 outstanding shares.
The largest institutional shareholders of Protara Therapeutics, Inc. - Common Stock (TARA) together control 68% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 10% | 5,141,616 | +22% | 0.01% | $27,379,105 |
| Velan Capital Investment Management LP | 5.5% | 2,834,652 | +33% | 8.8% | $15,108,695 |
| BlackRock, Inc. | 4.7% | 2,408,868 | +8.1% | 0% | $12,839,267 |
| VANGUARD GROUP INC | 4.7% | 2,391,903 | +26% | 0% | $12,748,844 |
| Integral Health Asset Management, LLC | 4.4% | 2,250,000 | +61% | 0.61% | $11,992,500 |
| Blackstone Inc. | 3.7% | 1,909,662 | 0% | 0.04% | $10,178,498 |
| ACORN CAPITAL ADVISORS, LLC | 3.4% | 1,752,115 | 0% | 3.2% | $9,338,773 |
| Sio Capital Management, LLC | 3.3% | 1,715,394 | 1.5% | $9,143,050 | |
| Catalio Capital Management, LP | 2.8% | 1,446,254 | -3.6% | 1.4% | $7,708,534 |
| 5AM Venture Management, LLC | 2.7% | 1,369,782 | +71% | 2.3% | $7,300,938 |
| Driehaus Capital Management LLC | 2.4% | 1,259,427 | +183% | 0.05% | $6,712,746 |
| UBS Group AG | 2.4% | 1,215,537 | +44% | 0% | $6,478,812 |
| ADAR1 Capital Management, LLC | 2.2% | 1,136,799 | +3127% | 0.45% | $6,059,139 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2% | 1,043,478 | 0.01% | $5,561,738 | |
| BAKER BROS. ADVISORS LP | 1.9% | 971,614 | +81% | 0.03% | $5,178,703 |
| CITADEL ADVISORS LLC | 1.8% | 901,541 | +79% | 0% | $4,805,214 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.6% | 817,196 | +7.7% | 0% | $4,356,728 |
| Maven Securities LTD | 1.5% | 754,626 | 0.51% | $4,022,157 | |
| MILLENNIUM MANAGEMENT LLC | 1.5% | 753,302 | +9.5% | 0% | $4,015,100 |
| SPHERA FUNDS MANAGEMENT LTD. | 1.3% | 650,000 | 0.72% | $3,464,500 | |
| MARSHALL WACE, LLP | 1.1% | 584,528 | +105% | 0% | $3,115,534 |
| STATE STREET CORP | 1.1% | 570,878 | +63% | 0% | $3,042,780 |
| BANK OF AMERICA CORP /DE/ | 0.96% | 495,904 | +175% | 0% | $2,643,169 |
| BURKEHILL GLOBAL MANAGEMENT, LP | 0.88% | 450,000 | 0.16% | $2,398,500 | |
| SUPERSTRING CAPITAL MANAGEMENT LP | 0.7% | 360,000 | 0% | 1% | $1,918,800 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 39,817,794 | $212,205,829 | +$73,079,091 | $5.33 | 103 |
| 2025 Q3 | 26,208,473 | $113,965,432 | -$10,353,742 | $4.35 | 79 |
| 2025 Q2 | 29,714,732 | $90,054,436 | +$447,680 | $3.03 | 76 |
| 2025 Q1 | 28,759,849 | $123,767,729 | -$8,349,026 | $4.26 | 59 |
| 2024 Q4 | 29,670,168 | $156,599,526 | +$91,818,405 | $5.28 | 60 |
| 2024 Q3 | 10,445,706 | $19,115,471 | +$384,364 | $1.83 | 33 |
| 2024 Q2 | 10,449,817 | $22,236,374 | +$12,029,265 | $2.08 | 38 |
| 2024 Q1 | 4,570,660 | $18,342,843 | +$911,041 | $4.01 | 34 |
| 2023 Q4 | 4,357,920 | $8,168,237 | -$1,261,027 | $1.88 | 30 |
| 2023 Q3 | 5,117,943 | $8,547,441 | -$31,849 | $1.67 | 31 |
| 2023 Q2 | 5,136,537 | $12,262,078 | -$1,134,644 | $2.39 | 28 |
| 2023 Q1 | 5,503,158 | $16,886,987 | +$77,617 | $3.13 | 28 |
| 2022 Q4 | 5,478,113 | $14,679,319 | -$481,288 | $2.68 | 29 |
| 2022 Q3 | 5,656,228 | $16,718,296 | -$789,370 | $2.96 | 26 |
| 2022 Q2 | 5,927,042 | $18,391,293 | -$2,063,463 | $2.93 | 31 |
| 2022 Q1 | 6,495,468 | $33,192,511 | -$1,990,162 | $5.11 | 34 |
| 2021 Q4 | 6,872,165 | $46,492,675 | +$3,840,591 | $6.75 | 36 |
| 2021 Q3 | 6,311,961 | $43,679,692 | -$8,598,514 | $6.92 | 36 |
| 2021 Q2 | 7,110,843 | $69,259,000 | -$22,850,218 | $9.74 | 38 |
| 2021 Q1 | 8,528,460 | $134,015,000 | -$11,645,346 | $15.74 | 49 |
| 2020 Q4 | 8,775,745 | $212,476,065 | -$5,829,365 | $24.21 | 48 |
| 2020 Q3 | 9,281,283 | $156,208,097 | +$91,825,921 | $16.83 | 44 |
| 2020 Q2 | 3,696,566 | $108,380,809 | +$108,380,809 | $29.32 | 31 |