NEKTAR THERAPEUTICS - Common Stock, $0.0001 par value per share (NKTR) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2025 to Q4 2025

Type / Class
Equity / Common Stock, $0.0001 par value per share
Symbol
NKTR on Nasdaq
Shares outstanding
20,249,175
Price per share
$42.28
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
17,311,463
Total reported value
$731,898,688
% of total 13F portfolios
0%
Share change
+2,453,488
Value change
+$83,237,770
Number of holders
171
Price from insider filings
$42.28
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of NEKTAR THERAPEUTICS - Common Stock, $0.0001 par value per share (NKTR) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
BIOTECHNOLOGY VALUE FUND L P 7.4% $32,978,662 1,276,595 BVF PARTNERS L P/IL 01 Jul 2025
VANGUARD GROUP INC 5% +1.2% $43,425,528 +$3,316,543 1,027,089 +8.3% The Vanguard Group 31 Dec 2025
SUSQUEHANNA SECURITIES, LLC 4% -38% $34,245,405 -$18,006,925 809,967 -34% G1 Execution Services, LLC 31 Dec 2025
INTEGRATED CORE STRATEGIES (US) LLC 3% -48% $32,489,559 -$20,590,346 570,994 -39% Millennium Management LLC 30 Sep 2025
Nantahala Capital Management, LLC 2.2% -59% $23,813,902 -$16,571,499 418,522 -41% Nantahala Capital Management, LLC 30 Sep 2025
BlackRock, Inc. 1.6% $5,245,655 203,017 BlackRock, Inc. 30 Jun 2025

As of 31 Dec 2025, 171 institutional investors reported holding 17,311,463 shares of NEKTAR THERAPEUTICS - Common Stock, $0.0001 par value per share (NKTR). This represents 85% of the company’s total 20,249,175 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of NEKTAR THERAPEUTICS - Common Stock, $0.0001 par value per share (NKTR) together control 59% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BVF INC/IL 7.7% 1,559,595 +22% 2.2% $65,939,677
VANGUARD GROUP INC 5.1% 1,027,089 +8.3% 0% $43,425,322
Two Seas Capital LP 3.7% 745,185 1.8% $31,506,422
BlackRock, Inc. 3.2% 645,607 +6% 0% $27,296,262
ARMISTICE CAPITAL, LLC 2.9% 596,000 +122% 0.62% $25,198,880
MORGAN STANLEY 2.8% 566,421 -39% 0% $23,948,280
Prosight Management, LP 2.7% 554,633 4.8% $23,449,883
TWO SIGMA INVESTMENTS, LP 2.3% 473,014 +8.9% 0.03% $19,999,032
Invesco Ltd. 2.3% 468,159 +106% 0% $19,793,774
MILLENNIUM MANAGEMENT LLC 2.2% 454,075 -17% 0.01% $19,198,291
Sofinnova Investments, Inc. 2.2% 438,630 +270% 0.8% $18,545,276
Point72 Asset Management, L.P. 2.1% 433,419 +250% 0.03% $18,324,955
EMERALD ADVISERS, LLC 1.9% 384,342 +19% 0.5% $16,249,980
SUSQUEHANNA INTERNATIONAL GROUP, LLP 1.9% 383,310 -59% 0.02% $16,206,346
22NW, LP 1.6% 331,115 0% 11% $13,999,542
Qube Research & Technologies Ltd 1.6% 323,915 +8051% 0.02% $13,695,126
CITADEL ADVISORS LLC 1.5% 309,777 -14% 0.01% $13,097,371
TWO SIGMA ADVISERS, LP 1.5% 308,414 +72% 0.03% $13,039,744
VOLORIDGE INVESTMENT MANAGEMENT, LLC 1.5% 295,716 +72% 0.04% $12,502,872
UBS Group AG 1.4% 287,561 +217% 0% $12,158,079
Balyasny Asset Management L.P. 1.4% 282,021 +54% 0.02% $11,923,848
PRIMECAP MANAGEMENT CO/CA/ 1.4% 280,150 -3.1% 0.01% $11,844,742
GEODE CAPITAL MANAGEMENT, LLC 1.3% 254,361 +13% 0% $10,757,656
EMERALD MUTUAL FUND ADVISERS TRUST 1.3% 253,125 +8.5% 0.52% $10,702,125
JANE STREET GROUP, LLC 1.1% 218,337 0.01% $9,231,289

Institutional Holders of NEKTAR THERAPEUTICS - Common Stock, $0.0001 par value per share (NKTR) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 17,311,463 $731,898,688 +$83,237,770 $42.28 171
2025 Q3 14,405,809 $819,769,158 +$415,987,343 $56.90 143
2025 Q2 7,657,053 $197,846,106 +$197,839,388 $25.84 100