Kalaris Therapeutics, Inc. - Common Stock, $0.0001 par value per share (KLRS) Institutional Ownership

13F Institutional Holders and Ownership History from Q1 2025 to Q4 2025

Type / Class
Equity / Common Stock, $0.0001 par value per share
Symbol
KLRS on Nasdaq
Shares outstanding
22,927,577
Price per share
$9.85
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
17,996,162
Total reported value
$151,883,912
% of total 13F portfolios
0%
Share change
+4,531,984
Value change
+$39,427,360
Number of holders
51
Price from insider filings
$9.85
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Kalaris Therapeutics, Inc. - Common Stock, $0.0001 par value per share (KLRS) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Samsara BioCapital, L.P. 56% -7.7% $90,804,603 +$10,553,555 12,953,581 +13% Srinivas Akkaraju 22 Dec 2025
RTW INVESTMENTS, LP 5.7% $12,714,000 1,300,000 RTW Investments, LP 31 Dec 2025
GILEAD SCIENCES, INC. 3.9% $4,715,740 723,273 GILEAD SCIENCES, INC. 18 Mar 2025
Invus Global Management, LLC 1.5% $754,533 282,586 Invus Public Equities, L.P. 30 Jun 2025
EcoR1 Capital, LLC 1.1% $1,315,201 201,718 EcoR1 Capital, LLC 31 Mar 2025

As of 31 Dec 2025, 51 institutional investors reported holding 17,996,162 shares of Kalaris Therapeutics, Inc. - Common Stock, $0.0001 par value per share (KLRS). This represents 78% of the company’s total 22,927,577 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Kalaris Therapeutics, Inc. - Common Stock, $0.0001 par value per share (KLRS) together control 77% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
SAMSARA BIOCAPITAL, LLC 56% 12,948,081 +13% 11% $109,281,804
RTW INVESTMENTS, LP 5.7% 1,300,000 0.11% $10,972,000
Paradigm Biocapital Advisors LP 3.1% 700,000 0.16% $5,908,000
Siren, L.L.C. 1.9% 435,798 +37% 0.11% $3,678,135
Alyeska Investment Group, L.P. 1.8% 403,551 0.01% $3,402,109
Ikarian Capital, LLC 1.6% 360,000 0.4% $3,038,401
VANGUARD GROUP INC 1.3% 292,790 +44% 0% $2,471,147
Kalehua Capital Management LLC 0.61% 139,901 0% 1.2% $1,180,764
ADAR1 Capital Management, LLC 0.44% 100,000 0.06% $844,000
Woodline Partners LP 0.44% 100,000 -59% 0% $844,000
WHI TRUST Co LLC 0.43% 97,493 0% 0.63% $822,841
BOOTHBAY FUND MANAGEMENT, LLC 0.4% 92,261 0.02% $778,683
RAYMOND JAMES FINANCIAL INC 0.39% 88,436 0% $746,400
RENAISSANCE TECHNOLOGIES LLC 0.38% 87,751 -22% 0% $740,618
Redmile Group, LLC 0.36% 82,955 0% 0.05% $700,140
GEODE CAPITAL MANAGEMENT, LLC 0.36% 82,647 +28% 0% $697,599
683 Capital Management, LLC 0.35% 80,590 0.06% $680,180
MARSHALL WACE, LLP 0.32% 72,876 +416% 0% $615,074
Propel Bio Management, LLC 0.18% 42,053 0.3% $354,927
Fortis Capital Advisors, LLC 0.17% 40,000 0% 0.05% $337,600
Belpointe Asset Management LLC 0.17% 40,000 0% 0.01% $337,600
BlackRock, Inc. 0.17% 38,454 -4.8% 0% $324,552
GOLDMAN SACHS GROUP INC 0.15% 34,303 +53% 0% $289,518
JANE STREET GROUP, LLC 0.14% 33,114 0% $279,482
OMERS ADMINISTRATION Corp 0.13% 30,000 0% $253,200

Institutional Holders of Kalaris Therapeutics, Inc. - Common Stock, $0.0001 par value per share (KLRS) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 17,996,162 $151,883,912 +$39,427,360 $8.44 51
2025 Q3 13,222,873 $76,428,251 +$1,455,559 $5.78 31
2025 Q2 13,362,268 $35,677,274 -$2,639,077 $2.67 29
2025 Q1 13,874,350 $111,411,096 +$111,410,076 $8.03 31