| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 20% | $383,922,060 | 11,971,377 | RA Capital Management, L.P. | 06 Mar 2025 | |||
| JANUS HENDERSON GROUP PLC | 8.9% | -11% | $73,836,251 | -$9,432,245 | 5,350,453 | -11% | JANUS HENDERSON GROUP PLC | 31 Dec 2025 |
| STATE STREET CORP | 6.4% | $53,184,524 | 3,853,951 | STATE STREET CORPORATION | 31 Dec 2025 | |||
| FMR LLC | 5.8% | $48,484,949 | 3,512,384 | FMR LLC | 31 Dec 2025 | |||
| BlackRock, Inc. | 5.7% | $77,284,838 | 3,345,664 | BlackRock, Inc. | 30 Jun 2025 | |||
| Prosight Management, LP | 5.3% | $43,569,636 | 3,157,220 | W. Lawrence Hawkins | 03 Feb 2026 | |||
| Paradigm Biocapital Advisors LP | 4.9% | -18% | $73,444,489 | -$14,982,559 | 2,920,258 | -17% | Paradigm BioCapital Advisors LP | 30 Jun 2025 |
| Adage Capital Management, L.P. | 4.3% | -21% | $63,503,750 | -$13,499,262 | 2,525,000 | -18% | Adage Capital Management, L.P. | 30 Jun 2025 |
As of 31 Dec 2025, 171 institutional investors reported holding 62,143,542 shares of Janux Therapeutics, Inc. - Common Stock (JANX). This represents 103% of the company’s total 60,117,449 outstanding shares.
The largest institutional shareholders of Janux Therapeutics, Inc. - Common Stock (JANX) together control 86% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 19% | 11,189,693 | 0% | 1.6% | $154,417,763 |
| JANUS HENDERSON GROUP PLC | 8.9% | 5,350,453 | +14% | 0.03% | $73,850,341 |
| BlackRock, Inc. | 6.8% | 4,080,200 | +9.4% | 0% | $56,306,760 |
| STATE STREET CORP | 6.4% | 3,853,951 | +104% | 0% | $53,184,524 |
| FMR LLC | 5.8% | 3,512,384 | -61% | 0% | $48,470,898 |
| VANGUARD GROUP INC | 4.8% | 2,906,386 | +20% | 0% | $40,108,126 |
| Prosight Management, LP | 4% | 2,392,523 | +176% | 6.8% | $33,016,817 |
| ORBIMED ADVISORS LLC | 3.3% | 1,954,426 | +11% | 0.58% | $26,971,079 |
| TCG Crossover Management, LLC | 3% | 1,789,617 | 0.82% | $24,696,715 | |
| WELLINGTON MANAGEMENT GROUP LLP | 2.7% | 1,610,186 | +130% | 0% | $22,220,567 |
| Alyeska Investment Group, L.P. | 2.2% | 1,301,089 | +206% | 0.05% | $17,955,028 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.9% | 1,113,582 | +2.7% | 0% | $15,370,581 |
| CITADEL ADVISORS LLC | 1.8% | 1,104,144 | +38% | 0.01% | $15,237,187 |
| GOLDMAN SACHS GROUP INC | 1.8% | 1,073,656 | +64% | 0% | $14,816,453 |
| Woodline Partners LP | 1.7% | 1,027,221 | +0.03% | 0.05% | $14,175,650 |
| Logos Global Management LP | 1.7% | 1,000,000 | +7% | 0.92% | $13,800,000 |
| Point72 Asset Management, L.P. | 1.6% | 961,819 | -44% | 0.02% | $13,273,102 |
| READYSTATE ASSET MANAGEMENT LP | 1.5% | 885,895 | -7.8% | 0.54% | $12,225,351 |
| Balyasny Asset Management L.P. | 1.5% | 885,551 | 0.02% | $12,220,604 | |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.2% | 744,466 | -41% | 0% | $10,274,000 |
| BANK OF AMERICA CORP /DE/ | 1.2% | 738,330 | +50% | 0% | $10,188,954 |
| Cormorant Asset Management, LP | 1.1% | 650,000 | -24% | 0.51% | $8,970,000 |
| MORGAN STANLEY | 1% | 618,385 | +25% | 0% | $8,533,727 |
| UBS Group AG | 0.98% | 590,060 | +51% | 0% | $8,142,828 |
| JANE STREET GROUP, LLC | 0.9% | 540,233 | +564% | 0.01% | $7,455,216 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 62,143,542 | $857,606,904 | -$104,019,467 | $13.80 | 171 |
| 2025 Q3 | 65,065,945 | $1,590,036,358 | -$3,819,977 | $24.44 | 170 |
| 2025 Q2 | 65,389,958 | $1,510,522,459 | -$28,053,981 | $23.10 | 169 |
| 2025 Q1 | 66,482,175 | $1,805,570,973 | -$17,647,630 | $27.00 | 179 |
| 2024 Q4 | 64,089,510 | $3,430,809,553 | +$1,001,839,547 | $53.54 | 213 |
| 2024 Q3 | 45,621,730 | $2,072,353,785 | +$42,332,014 | $45.43 | 158 |
| 2024 Q2 | 44,723,442 | $1,873,142,325 | +$107,659,314 | $41.89 | 153 |
| 2024 Q1 | 42,327,541 | $1,593,608,078 | +$334,250,630 | $37.65 | 118 |
| 2023 Q4 | 33,501,695 | $359,539,970 | -$17,204,195 | $10.73 | 64 |
| 2023 Q3 | 35,112,124 | $353,984,587 | +$45,518,472 | $10.08 | 57 |
| 2023 Q2 | 30,508,831 | $362,117,070 | -$408,523 | $11.87 | 54 |
| 2023 Q1 | 30,541,873 | $369,527,936 | +$18,629,245 | $12.10 | 48 |
| 2022 Q4 | 28,954,042 | $381,308,644 | -$7,758,264 | $13.17 | 49 |
| 2022 Q3 | 29,548,436 | $400,093,845 | +$8,918,649 | $13.54 | 45 |
| 2022 Q2 | 28,911,820 | $352,963,471 | +$6,297,905 | $12.21 | 43 |
| 2022 Q1 | 28,388,419 | $407,113,023 | +$11,406,319 | $14.34 | 46 |
| 2021 Q4 | 27,496,946 | $541,627,745 | +$19,103,067 | $19.73 | 46 |
| 2021 Q3 | 26,499,088 | $571,208,440 | +$35,499,490 | $21.63 | 44 |
| 2021 Q2 | 24,743,225 | $614,460,000 | +$614,460,000 | $24.95 | 29 |