Day One Biopharmaceuticals, Inc. - Common Stock, par value $0.0001 per share (DAWN) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2021 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.0001 per share
Symbol
DAWN on Nasdaq
Shares outstanding
101,960,784
Price per share
$11.78
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
81,357,272
Total reported value
$757,944,144
% of total 13F portfolios
0%
Share change
-4,345,472
Value change
-$18,862,257
Number of holders
180
Price from insider filings
$11.78
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Day One Biopharmaceuticals, Inc. - Common Stock, par value $0.0001 per share (DAWN) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
BlackRock, Inc. 5.8% +22% $38,061,315 +$6,751,002 5,849,917 +22% BlackRock, Inc. 30 Jun 2025
FMR LLC 5.6% -43% $53,284,798 -$40,829,513 5,717,008 -43% FMR LLC 31 Dec 2025
Vestal Point Capital, LP 5.1% $55,068,000 5,200,000 Vestal Point Capital, LP 31 Dec 2025

As of 31 Dec 2025, 180 institutional investors reported holding 81,357,272 shares of Day One Biopharmaceuticals, Inc. - Common Stock, par value $0.0001 per share (DAWN). This represents 80% of the company’s total 101,960,784 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Day One Biopharmaceuticals, Inc. - Common Stock, par value $0.0001 per share (DAWN) together control 64% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BlackRock, Inc. 8.7% 8,837,574 -1.8% 0% $82,366,188
Atlas Venture Life Science Advisors, LLC 6.3% 6,412,560 -0.28% 6.9% $59,765,059
VANGUARD GROUP INC 6.2% 6,282,376 +1.6% 0% $58,551,745
FMR LLC 5.6% 5,717,008 -43% 0% $53,282,512
Vestal Point Capital, LP 5.1% 5,200,000 +94% 1.8% $48,464,000
STATE STREET CORP 4.2% 4,289,566 +32% 0% $39,978,755
DEERFIELD MANAGEMENT COMPANY, L.P. 3.7% 3,723,131 -21% 0.44% $34,699,581
Pictet Asset Management Holding SA 2.9% 2,990,801 +26% 0.03% $27,874,265
AIGH Capital Management LLC 2% 1,992,021 +31% 5.5% $18,565,635
GEODE CAPITAL MANAGEMENT, LLC 1.8% 1,877,838 +6.6% 0% $17,504,632
Hudson Bay Capital Management LP 1.7% 1,700,000 +29% 0.09% $15,844,000
MORGAN STANLEY 1.5% 1,550,274 +19% 0% $14,448,557
GOLDMAN SACHS GROUP INC 1.5% 1,506,234 +9.8% 0% $14,038,100
Balyasny Asset Management L.P. 1.5% 1,489,924 +7.6% 0.03% $13,886,092
Qube Research & Technologies Ltd 1.5% 1,486,562 +27% 0.02% $13,854,758
CITADEL ADVISORS LLC 1.3% 1,359,613 +105% 0.01% $12,671,593
MILLENNIUM MANAGEMENT LLC 1.3% 1,349,919 +95% 0.01% $12,581,245
RENAISSANCE TECHNOLOGIES LLC 1.3% 1,305,084 +44% 0.02% $12,163,383
Jefferies Financial Group Inc. 1.1% 1,121,502 0.09% $10,452,399
BANK OF AMERICA CORP /DE/ 1.1% 1,083,818 -9.1% 0% $10,101,185
DIMENSIONAL FUND ADVISORS LP 1% 1,037,312 -15% 0% $9,666,870
DAFNA Capital Management LLC 0.98% 999,163 0% 2.2% $9,312,199
JANE STREET GROUP, LLC 0.83% 845,154 +203% 0.01% $7,876,835
MAK CAPITAL ONE LLC 0.81% 826,205 -43% 1% $7,700,231
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.72% 737,660 +2457% 0.01% $6,874,991

Institutional Holders of Day One Biopharmaceuticals, Inc. - Common Stock, par value $0.0001 per share (DAWN) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 81,357,272 $757,944,144 -$18,862,257 $9.32 180
2025 Q3 85,449,652 $602,397,711 -$3,593,530 $7.05 169
2025 Q2 86,186,499 $560,206,343 -$67,566,968 $6.50 173
2025 Q1 94,058,917 $745,890,533 -$40,487,714 $7.93 183
2024 Q4 93,739,417 $1,187,690,667 -$5,879,821 $12.67 163
2024 Q3 92,050,053 $1,283,687,781 +$239,491,695 $13.93 165
2024 Q2 74,705,046 $1,029,464,955 +$17,373,333 $13.78 155
2024 Q1 72,782,347 $1,202,300,406 -$58,498,635 $16.52 147
2023 Q4 76,570,666 $1,117,957,204 -$50,224,829 $14.60 138
2023 Q3 77,547,732 $951,517,363 -$22,223,998 $12.27 127
2023 Q2 78,803,713 $941,011,552 +$208,122,003 $11.94 136
2023 Q1 61,209,087 $818,137,120 -$10,189,943 $13.37 122
2022 Q4 59,797,551 $1,286,831,022 -$37,719,296 $21.52 105
2022 Q3 60,343,678 $1,208,648,617 +$24,007,409 $20.03 87
2022 Q2 59,307,013 $1,061,573,186 +$302,547,160 $17.90 80
2022 Q1 43,302,427 $429,553,897 +$13,144,675 $9.92 66
2021 Q4 41,477,196 $698,277,000 +$74,959,681 $16.85 57
2021 Q3 19,043,827 $450,147,328 +$32,649,130 $23.73 43
2021 Q2 17,724,839 $401,085,000 +$401,084,962 $22.77 32