ARDELYX, INC. - Common Stock (ARDX) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2014 to Q4 2025

Type / Class
Equity / Common Stock
Symbol
ARDX on Nasdaq
Shares outstanding
243,015,147
Price per share
$7.89
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
166,643,681
Total reported value
$971,606,309
% of total 13F portfolios
0%
Share change
-4,037,445
Value change
-$19,556,176
Number of holders
225
Price from insider filings
$7.89
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of ARDELYX, INC. - Common Stock (ARDX) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
VANGUARD GROUP INC 7.8% +16% $110,650,386 +$17,185,872 18,979,483 +18% The Vanguard Group 31 Dec 2025
JANUS HENDERSON GROUP PLC 5.7% -10% $76,170,752 -$6,798,497 13,824,093 -8.2% JANUS HENDERSON GROUP PLC 30 Sep 2025
INTEGRATED CORE STRATEGIES (US) LLC 5.4% $76,499,983 13,121,781 Millennium Management LLC 05 Jan 2026
STATE STREET CORP 4.9% $63,181,381 11,592,914 STATE STREET CORPORATION 31 Dec 2024
MILLENNIUM MANAGEMENT LLC 3.2% -38% $42,272,648 -$24,398,060 7,671,987 -37% Millennium Management LLC 30 Sep 2025

As of 31 Dec 2025, 225 institutional investors reported holding 166,643,681 shares of ARDELYX, INC. - Common Stock (ARDX). This represents 69% of the company’s total 243,015,147 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of ARDELYX, INC. - Common Stock (ARDX) together control 56% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BlackRock, Inc. 8.7% 21,139,105 +1.5% 0% $123,240,982
VANGUARD GROUP INC 7.8% 18,979,483 +3.3% 0% $110,650,386
JANUS HENDERSON GROUP PLC 6% 14,514,692 +5% 0.04% $84,583,285
STATE STREET CORP 4.9% 11,912,339 +23% 0% $69,448,936
MILLENNIUM MANAGEMENT LLC 4.9% 11,909,511 +56% 0.05% $69,432,449
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 3.8% 9,328,744 0% 0.08% $54,387,000
GEODE CAPITAL MANAGEMENT, LLC 2.4% 5,827,618 +1.2% 0% $33,980,836
MARSHALL WACE, LLP 2.1% 5,188,639 -42% 0.03% $30,249,766
Nuveen, LLC 2.1% 5,164,549 -0.2% 0.01% $30,109,321
GOLDMAN SACHS GROUP INC 1.3% 3,064,746 +19% 0% $17,867,469
TWO SIGMA INVESTMENTS, LP 1.2% 2,873,969 +15% 0.02% $16,755,239
MORGAN STANLEY 0.97% 2,358,806 -18% 0% $13,751,843
Rock Springs Capital Management LP 0.95% 2,299,473 +0.58% 0.69% $13,405,928
BANK OF AMERICA CORP /DE/ 0.91% 2,208,693 -17% 0% $12,876,677
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.87% 2,117,293 -3.5% 0% $12,343,818
JANE STREET GROUP, LLC 0.85% 2,060,667 -6.1% 0.01% $12,013,689
AQR CAPITAL MANAGEMENT LLC 0.83% 2,025,083 -5.6% 0.01% $11,806,235
NORTHERN TRUST CORP 0.83% 2,019,285 -4.7% 0% $11,772,430
ORACLE INVESTMENT MANAGEMENT INC 0.77% 1,872,624 +25% 7.2% $10,917,398
JONES FINANCIAL COMPANIES LLLP 0.76% 1,854,755 -1% 0.01% $10,813,222
RENAISSANCE TECHNOLOGIES LLC 0.74% 1,794,793 +6.2% 0.02% $10,463,643
Eversept Partners, LP 0.71% 1,715,129 +20% 0.56% $9,999,202
J. Goldman & Co LP 0.67% 1,622,736 +1693% 0.37% $9,460,551
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.59% 1,424,878 +146% 0% $8,307,039
D. E. Shaw & Co., Inc. 0.58% 1,411,267 -57% 0.01% $8,227,687

Institutional Holders of ARDELYX, INC. - Common Stock (ARDX) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 166,643,681 $971,606,309 -$19,556,176 $5.83 225
2025 Q3 161,744,278 $891,308,863 -$30,405,809 $5.51 221
2025 Q2 167,710,260 $657,039,970 +$8,960,616 $3.92 203
2025 Q1 164,576,582 $808,416,494 +$58,328,254 $4.91 220
2024 Q4 150,859,849 $764,834,270 +$39,500,927 $5.07 211
2024 Q3 141,707,765 $975,933,629 -$20,620,523 $6.89 200
2024 Q2 144,224,130 $1,068,439,534 +$27,386,203 $7.41 194
2024 Q1 140,660,510 $1,026,744,623 +$30,824,013 $7.30 187
2023 Q4 136,969,310 $849,140,365 +$78,952,256 $6.20 158
2023 Q3 125,847,784 $513,505,151 +$7,178,966 $4.08 150
2023 Q2 125,431,955 $425,166,678 +$30,557,318 $3.39 144
2023 Q1 113,675,323 $544,693,922 +$165,294,361 $4.79 129
2022 Q4 78,419,304 $223,207,438 +$72,727,186 $2.85 98
2022 Q3 66,773,937 $79,510,458 +$36,649,057 $1.19 78
2022 Q2 38,015,789 $22,668,222 -$3,885,722 $0.59 72
2022 Q1 39,645,840 $42,412,652 -$2,239,091 $1.07 85
2021 Q4 41,835,051 $46,015,167 -$11,862,592 $1.10 95
2021 Q3 48,724,792 $64,486,313 -$260,541,309 $1.32 98
2021 Q2 84,843,798 $643,129,955 +$1,702,726 $7.58 120
2021 Q1 84,628,144 $559,673,700 +$30,418,660 $6.62 120
2020 Q4 80,265,333 $519,321,662 +$11,395,260 $6.47 118
2020 Q3 77,475,843 $406,751,205 -$2,248,690 $5.25 107
2020 Q2 77,584,170 $536,863,818 +$8,872,855 $6.92 124
2020 Q1 76,585,606 $435,405,838 +$6,098,633 $5.68 97
2019 Q4 74,902,472 $562,054,462 +$190,640,786 $7.50 99
2019 Q3 48,538,260 $228,132,563 +$14,809,114 $4.70 75
2019 Q2 45,635,669 $122,755,737 +$472,108 $2.69 68
2019 Q1 46,045,418 $128,928,009 -$1,854,970 $2.80 70
2018 Q4 47,034,986 $84,190,187 -$5,219,040 $1.79 79
2018 Q3 46,855,283 $203,766,011 +$4,634,248 $4.35 83
2018 Q2 45,978,418 $170,134,619 +$35,639,609 $3.70 92
2018 Q1 35,214,226 $177,834,754 -$2,783,994 $5.05 76
2017 Q4 35,332,779 $233,188,055 -$2,143,937 $6.60 77
2017 Q3 36,166,771 $202,824,651 -$5,993,195 $5.60 80
2017 Q2 37,274,451 $190,018,355 -$32,515,051 $5.10 86
2017 Q1 38,633,288 $488,989,366 +$17,406,705 $12.65 79
2016 Q4 38,631,665 $548,578,881 -$1,007,303 $14.20 84
2016 Q3 38,571,940 $499,111,978 +$119,338,460 $12.94 74
2016 Q2 29,693,264 $259,217,119 -$1,192,811 $8.73 63
2016 Q1 29,871,501 $232,083,000 +$63,001,460 $7.77 65
2015 Q4 21,376,384 $387,382,681 +$1,606,263 $18.12 65
2015 Q3 21,193,642 $366,184,616 +$8,942,743 $17.28 54
2015 Q2 20,722,631 $329,379,904 +$141,921,247 $15.97 57
2015 Q1 11,799,898 $154,447,933 +$9,578,673 $13.09 49
2014 Q4 10,866,742 $205,269,616 +$11,041,336 $18.89 50
2014 Q3 10,368,074 $147,326,000 +$138,806,934 $14.21 32
2014 Q2 579,155 $9,477,000 +$9,115,000 $15.97 5