ALUMIS INC. - Common Stock, $0.0001 par value per share (ALMS) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2024 to Q4 2025

Type / Class
Equity / Common Stock, $0.0001 par value per share
Symbol
ALMS on Nasdaq
Shares outstanding
117,504,056
Price per share
$26.84
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
78,898,300
Total reported value
$770,051,253
% of total 13F portfolios
0%
Share change
+3,568,564
Value change
+$72,305,373
Number of holders
131
Price from insider filings
$26.84
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of ALUMIS INC. - Common Stock, $0.0001 par value per share (ALMS) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Foresite Capital Fund VI LP 14% -11% $158,014,106 +$9,680,555 16,189,804 +6.5% James B. Tananbaum 08 Jan 2026
AyurMaya Capital Management Company, LP 16% -29% $65,554,931 +$19,457,899 15,139,707 +42% AyurMaya Capital Management Company, LP 21 May 2025
Samsara BioCapital, L.P. 5.4% +2% $61,929,972 +$11,811,946 6,345,219 +24% Srinivas Akkaraju 09 Jan 2026
venBio Global Strategic Fund IV, L.P. 4.8% $21,297,292 4,619,803 venBio Global Strategic Fund IV, L.P. 30 Jun 2025

As of 31 Dec 2025, 131 institutional investors reported holding 78,898,300 shares of ALUMIS INC. - Common Stock, $0.0001 par value per share (ALMS). This represents 67% of the company’s total 117,504,056 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of ALUMIS INC. - Common Stock, $0.0001 par value per share (ALMS) together control 61% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
AyurMaya Capital Management Company, LP 13% 15,139,706 0% 100% $147,763,531
Foresite Capital Management V, LLC 4.9% 5,779,348 0% 34% $56,406,436
SAMSARA BIOCAPITAL, LLC 4.9% 5,756,984 +20% 5.8% $56,188,164
venBio Partners LLC 3.9% 4,619,803 0% 21% $45,089,277
BlackRock, Inc. 3.9% 4,566,502 +8.9% 0% $44,569,059
Foresite Capital Management VI LLC 3.6% 4,247,670 0% 13% $41,457,259
VANGUARD GROUP INC 3.5% 4,103,290 +1.8% 0% $40,048,110
Cormorant Asset Management, LP 3.1% 3,635,596 +69% 2% $35,483,417
Saturn V Capital Management LP 2.7% 3,135,953 5.6% $30,606,901
Nextech Invest, Ltd. 2.5% 2,915,998 0% 2.8% $28,460,140
Octagon Capital Advisors LP 2.2% 2,530,700 3.1% $24,699,632
MPM BIOIMPACT LLC 2% 2,401,992 2.7% $23,443,442
SR One Capital Management, LP 1.7% 1,959,896 0% 2.7% $19,128,585
BAKER BROS. ADVISORS LP 1.3% 1,562,500 0% 0.09% $15,250,000
GEODE CAPITAL MANAGEMENT, LLC 1.3% 1,487,626 +6.8% 0% $14,522,800
STATE STREET CORP 1.1% 1,259,446 +14% 0% $12,292,193
MILLENNIUM MANAGEMENT LLC 0.98% 1,151,118 +263% 0.01% $11,234,912
ORBIMED ADVISORS LLC 0.94% 1,102,730 -43% 0.23% $10,762,645
Trium Capital LLP 0.76% 893,107 -71% 6.8% $8,716,724
Yu Fan 0.67% 789,618 0% 8.4% $7,706,672
Omega Fund Management, LLC 0.56% 653,223 0% 2.2% $6,375,456
Opaleye Management Inc. 0.46% 535,000 -20% 0.69% $5,221,600
MORGAN STANLEY 0.43% 506,529 +52% 0% $4,943,723
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.43% 504,075 +2.7% 0% $4,919,772
Siren, L.L.C. 0.43% 500,000 0.15% $4,880,000

Institutional Holders of ALUMIS INC. - Common Stock, $0.0001 par value per share (ALMS) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 78,898,300 $770,051,253 +$72,305,373 $9.76 131
2025 Q3 77,994,182 $311,197,950 -$66,383 $3.99 129
2025 Q2 78,328,492 $234,986,451 +$114,158,793 $3.00 112
2025 Q1 40,203,252 $246,848,226 -$2,907,402 $6.14 72
2024 Q4 40,261,542 $316,456,858 +$6,196,390 $7.86 64
2024 Q3 35,212,710 $376,073,647 +$60,319,979 $10.68 52
2024 Q2 28,575,030 $380,047,605 +$380,047,605 $13.30 29