| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Fairmount Funds Management LLC | 20% | 0% | $89,373,614 | +$26,797,898 | 10,353,875 | +43% | Fairmount Funds Management LLC | 06 Oct 2025 |
| Venrock Healthcare Capital Partners III, L.P. | 9.9% | 0% | $70,905,847 | +$26,271,533 | 5,115,862 | +59% | Venrock Healthcare Capital Partners III, L.P. | 31 Dec 2025 |
| FMR LLC | 15% | $40,965,976 | 4,735,951 | FMR LLC | 30 May 2025 | |||
| Bellevue Group AG | 6.8% | $46,307,688 | 3,341,103 | Bellevue Group AG | 16 Dec 2025 | |||
| RA CAPITAL MANAGEMENT, L.P. | 7% | +72% | $27,758,364 | +$16,318,579 | 3,214,969 | +143% | RA Capital Management, L.P. | 08 Oct 2025 |
| JANUS HENDERSON GROUP PLC | 6.2% | $42,459,514 | 3,063,457 | JANUS HENDERSON GROUP PLC | 31 Dec 2025 | |||
| BlackRock, Inc. | 6.6% | +26% | $18,565,068 | +$3,763,302 | 2,150,203 | +25% | BlackRock, Inc. | 30 Sep 2025 |
| VANGUARD GROUP INC | 4.2% | -23% | $32,337,685 | +$4,446,695 | 2,095,767 | +16% | The Vanguard Group | 31 Dec 2025 |
| Frazier Life Sciences Public Fund, L.P. | 4.2% | 0% | $11,949,495 | +$379,228 | 1,384,646 | +3.3% | Frazier Life Sciences Public Fund, L.P. | 30 Sep 2025 |
| TCG Crossover GP I, LLC | 0.2% | $649,193 | 64,023 | TCG Crossover GP I, LLC | 28 Apr 2025 | |||
| Atlas Venture Fund XII, L.P. | 0.2% | $521,257 | 51,406 | Atlas Venture Associates XII, L.P. | 28 Apr 2025 |
As of 31 Dec 2025, 102 institutional investors reported holding 47,075,378 shares of Jade Biosciences, Inc. - Common Stock, $0.0001 par value (JBIO). This represents 91% of the company’s total 51,675,374 outstanding shares.
The largest institutional shareholders of Jade Biosciences, Inc. - Common Stock, $0.0001 par value (JBIO) together control 84% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FMR LLC | 13% | 6,894,488 | +41% | 0.01% | $106,381,950 |
| Fairmount Funds Management LLC | 8.8% | 4,553,494 | +41% | 5.3% | $70,260,412 |
| RA CAPITAL MANAGEMENT, L.P. | 7.1% | 3,671,083 | +246% | 0.58% | $56,644,811 |
| Bellevue Group AG | 6.5% | 3,341,103 | 0.98% | $51,553,219 | |
| VR ADVISER, LLC | 6.2% | 3,220,364 | 0% | 2.5% | $49,690,217 |
| BlackRock, Inc. | 5.6% | 2,870,313 | +33% | 0% | $44,288,930 |
| VANGUARD GROUP INC | 4.1% | 2,095,767 | +21% | 0% | $32,337,685 |
| BAKER BROS. ADVISORS LP | 3.2% | 1,641,137 | 0.15% | $25,322,744 | |
| Remedium Capital Partners, LLC | 3.1% | 1,577,750 | 0% | 14% | $24,345,000 |
| Versant Venture Management, LLC | 3% | 1,525,820 | 0% | 16% | $23,543,403 |
| RTW INVESTMENTS, LP | 2.8% | 1,449,273 | 0% | 0.22% | $22,362,282 |
| Avidity Partners Management LP | 2.7% | 1,400,708 | +24% | 6.2% | $21,612,924 |
| SAMSARA BIOCAPITAL, LLC | 1.9% | 968,798 | +82% | 1.5% | $14,948,553 |
| Driehaus Capital Management LLC | 1.7% | 887,179 | -29% | 0.09% | $13,689,172 |
| MARSHALL WACE, LLP | 1.7% | 875,273 | +2199% | 0.01% | $13,505,462 |
| Aberdeen Group plc | 1.7% | 867,284 | 0.02% | $13,382,192 | |
| GEODE CAPITAL MANAGEMENT, LLC | 1.6% | 841,808 | +26% | 0% | $12,991,338 |
| GREAT POINT PARTNERS LLC | 1.6% | 806,273 | +27% | 4% | $12,440,792 |
| Soleus Capital Management, L.P. | 1.5% | 796,744 | 0% | 0.52% | $12,293,760 |
| Affinity Asset Advisors, LLC | 1.4% | 714,956 | +995% | 0.79% | $11,031,771 |
| STATE STREET CORP | 1.2% | 642,921 | +29% | 0% | $9,920,271 |
| Point72 Asset Management, L.P. | 1.1% | 558,474 | 0.01% | $8,617,254 | |
| ORBIMED ADVISORS LLC | 1% | 531,163 | 0% | 0.18% | $8,195,845 |
| Opaleye Management Inc. | 0.83% | 427,608 | 0.88% | $6,597,991 | |
| Logos Global Management LP | 0.76% | 395,000 | -37% | 0.41% | $6,094,850 |