ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.0001 per share (ACTU) Institutional Ownership

13F Institutional Holders and Ownership History from Q3 2024 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.0001 per share
Symbol
ACTU on Nasdaq
Shares outstanding
23,165,208
Price per share
$4.74
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
13,110,237
Total reported value
$80,234,480
% of total 13F portfolios
0%
Share change
+1,089,796
Value change
+$6,660,093
Number of holders
44
Price from insider filings
$4.74
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.0001 per share (ACTU) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
BIOS Fund I, LP 50% -2.9% $112,734,207 +$1,733,259 10,267,232 +1.6% AARON G.L. FLETCHER 27 Jun 2025
Voss Capital, LP 5.3% $8,471,516 1,227,756 Voss Capital, LP 15 Dec 2025

As of 31 Dec 2025, 44 institutional investors reported holding 13,110,237 shares of ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.0001 per share (ACTU). This represents 57% of the company’s total 23,165,208 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.0001 per share (ACTU) together control 56% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BIOS Capital Management, LP 43% 10,049,996 0% 74% $61,505,976
Voss Capital, LP 5.6% 1,300,000 +45% 0.42% $7,956,000
VANGUARD GROUP INC 2.3% 529,111 +67% 0% $3,238,159
BlackRock, Inc. 1.9% 432,041 +53% 0% $2,644,091
GEODE CAPITAL MANAGEMENT, LLC 0.9% 207,744 +43% 0% $1,271,393
NORTHERN TRUST CORP 0.44% 101,423 +19% 0% $620,709
Texas Capital Bank Wealth Management Services Inc 0.41% 94,592 0.03% $578,903
STATE STREET CORP 0.24% 56,290 +13% 0% $344,495
ROYAL BANK OF CANADA 0.15% 35,187 +173% 0% $215,000
BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.13% 30,982 0% $189,610
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.1% 23,841 +61% 0% $145,907
Rock Creek Group, LP 0.09% 21,759 0.02% $133,165
WELLS FARGO & COMPANY/MN 0.09% 20,146 +49% 0% $123,294
SFMG, LLC 0.09% 20,000 +18% 0.01% $122,400
Gleason Group, Inc. 0.08% 19,028 0% 0.01% $116,451
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 0.08% 18,518 -4.1% 0% $113,330
JANE STREET GROUP, LLC 0.07% 16,625 0% $101,745
BARCLAYS PLC 0.06% 14,946 +69% 0% $91,470
MORGAN STANLEY 0.06% 13,119 +72% 0% $80,289
LPL Financial LLC 0.06% 12,965 -20% 0% $79,346
Bank of New York Mellon Corp 0.05% 12,565 0% $76,898
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.04% 10,253 0% $62,748
RHUMBLINE ADVISERS 0.04% 9,534 +8.7% 0% $58,343
DEUTSCHE BANK AG\ 0.04% 9,309 +640% 0% $56,971
BANK OF AMERICA CORP /DE/ 0.04% 9,061 +86% 0% $55,454

Institutional Holders of ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.0001 per share (ACTU) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 13,110,237 $80,234,480 +$6,660,093 $6.12 44
2025 Q3 12,026,097 $80,455,749 +$5,410,880 $6.69 42
2025 Q2 11,217,203 $68,541,901 +$4,868,272 $6.11 38
2025 Q1 10,401,592 $70,445,498 +$1,934,199 $6.77 25
2024 Q4 10,116,136 $80,524,037 -$1,087,916 $7.96 19
2024 Q3 382,167 $2,847,155 +$2,847,155 $7.45 10