BAKER BROS. ADVISORS LP - 31 Dec 2025 SCHEDULE 13G/A Report for Stoke Therapeutics, Inc. Common Stock, par value $0.0001 per share (STOK)

Filing Manager: BAKER BROS. ADVISORS LP
Reporting Manager: Baker Bros. Advisors LP
Security: Stoke Therapeutics, Inc. Common Stock, par value $0.0001 per share
Symbol: STOK
Shares outstanding: 57,529,259 shares
Disclosed Ownership: 3,336,697 shares
Ownership: 5.8%
Form type: SCHEDULE 13G/A
Filing time: 17 Feb 2026, 16:13:34 UTC
Date of event: 31 Dec 2025
SEC: View on sec.gov

Reporting Managers (4)

Name	Ownership	Shares Owned	sole voting power	Signature	Title
Baker Bros. Advisors LP	5.8%	3,336,697	3,336,697	/s/ Scott L. Lessing	Scott L. Lessing/ President By: Baker Bros. Advisors (GP) LLC, its general partner
Baker Bros. Advisors (GP) LLC	5.8%	3,336,697	3,336,697	/s/ Scott L. Lessing	Scott L. Lessing/ President
Julian C. Baker	5.8%	3,336,697	3,336,697	/s/ Julian C. Baker	Julian C. Baker
Felix J. Baker	5.8%	3,336,697	3,336,697	/s/ Felix J. Baker	Felix J. Baker