ORBIMED ADVISORS LLC - 31 Dec 2025 SCHEDULE 13G/A Report for C4 Therapeutics, Inc. Common Stock, par value $0.0001 per share (CCCC)

Filing Manager: ORBIMED ADVISORS LLC
Reporting Manager: OrbiMed Capital LLC
Security: C4 Therapeutics, Inc. Common Stock, par value $0.0001 per share
Symbol: CCCC
Shares outstanding: 88,353,400 shares
Disclosed Ownership: 883,534 shares
Ownership: 1%
Form type: SCHEDULE 13G/A
Filing time: 17 Feb 2026, 18:18:34 UTC
Date of event: 31 Dec 2025
Previous filing: 14 Nov 2025
SEC: View on sec.gov

Reporting Managers (2)

Name	Ownership	Shares Owned	sole voting power	shared voting power	Signature	Title	CIK
OrbiMed Advisors LLC	0.5%	521,368	0	521,368	/s/ Carl L. Gordon	Carl L. Gordon/Member
OrbiMed Capital LLC	1%	883,534	883,534	0	/s/ Carl L. Gordon	Carl L. Gordon/Member