| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Bharucha David | Chief Medical Officer | C/O MILESTONE PHARMACEUTICALS INC., 1111 DR. FREDERIK-PHILIPS BLVD, STE 420, MONTREAL, QUEBEC, CANADA | /s/ Joseph Oliveto, Attorney-in-Fact | 04 Feb 2026 | 0001910985 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | MIST | Employee Stock Option (right to buy) | Award | $0 | +204,000 | $0.000000 | 204,000 | 02 Feb 2026 | Common Shares | 204,000 | $1.97 | Direct | F1 | |
| transaction | MIST | Restricted Stock Unit | Award | $0 | +136,000 | $0.000000 | 136,000 | 02 Feb 2026 | Common Shares | 136,000 | Direct | F2, F3 |
| Id | Content |
|---|---|
| F1 | One-fourth (1/4th) of the shares subject to the option vest on February 2, 2027, and one thirty-sixth (1/36th) of the remaining shares subject to this option shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date. |
| F2 | Each restricted stock unit represents a contingent right to receive one common share. |
| F3 | One-fourth (1/4th) of the shares subject to the restricted stock unit award vest on each of February 2, 2027, February 2, 2028, February 2, 2029 and February 2, 2030, subject to the Reporting Person continuing to provide service through each such date. |