| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Knight Jeff E. | Chief Operating Officer | C/O CRINETICS PHARMACEUTICALS, INC., 6055 LUSK BOULEVARD, SAN DIEGO | /s/ Tobin Schilke, as attorney-in-fact | 25 Feb 2026 | 0001881007 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CRNX | Common Stock | Award | $0 | +34,000 | +39% | $0.000000 | 121,929 | 23 Feb 2026 | Direct | F1, F2 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CRNX | Stock Option (Right to Buy) | Award | $0 | +55,000 | $0.000000 | 55,000 | 23 Feb 2026 | Common Stock | 55,000 | $43.79 | Direct | F3 |
| Id | Content |
|---|---|
| F1 | The transaction reported on this line involves the receipt of restricted stock units, which represent the right to receive shares of the Issuer's Common Stock, with 25% vesting annually beginning on March 1, 2027. |
| F2 | Includes 438 shares acquired under the Issuer's Employee Stock Purchase Plan. |
| F3 | The stock option shall vest and become exercisable in a series of forty-eight (48) successive equal monthly installments measured from the vesting commencement date of February 23, 2026. |