| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| ENRIGHT PATRICK G | Director, 10%+ Owner | C/O LONGITUDE CAPITAL, 2740 SAND HILL ROAD, SECOND FLOOR, MENLO PARK | /s/ Michael Greco, Attorney-in-Fact | 03 Feb 2026 | 0001253886 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| holding | MANE | Series B Convertible Preferred Stock | 03 Feb 2026 | Common Stock | 1,236,631 | See Footnote | F1, F2 | |||||||
| holding | MANE | Series C Convertible Preferred Stock | 03 Feb 2026 | Common Stock | 1,171,121 | See Footnote | F2, F3 | |||||||
| holding | MANE | Series C Convertible Preferred Stock | 03 Feb 2026 | Common Stock | 1,171,121 | See Footnote | F3, F4 |
| Id | Content |
|---|---|
| F1 | Each share of Series B Convertible Preferred Stock is convertible into shares of the Issuer's Common Stock on a 10.067-for-1 basis and has no expiration date. The Series B Convertible Preferred Stock will automatically convert into shares of the Issuer's Common Stock immediately prior to the closing of the Issuer's initial public offering. |
| F2 | These shares are held by Longitude Venture Partners V, L.P. ("LVPV"). Longitude Capital Partners V, LLC ("LCPV"), is the general partner of LVPV and may be deemed to have voting, investment and dispositive power with respect to these shares. Juliet Tammenoms Bakker and the Reporting Person, a member of the board of directors of the Issuer, are the managing members of LCPV, and may each be deemed to share voting, investment and dispositive power with respect to these shares. Each of LCPV, Ms. Tammenoms Bakker and the Reporting Person disclaims beneficial ownership of such shares except to the extent of their respective pecuniary interests therein. |
| F3 | Each share of Series C Convertible Preferred Stock is convertible into shares of the Issuer's Common Stock on a 10.067-for-1 basis and has no expiration date. The Series C Convertible Preferred Stock will automatically convert into shares of the Issuer's Common Stock immediately prior to the closing of the Issuer's initial public offering. |
| F4 | These shares are held by Longitude 103.8 East, L.P. ("L103"). Longitude 103.8 East Partners, LLC ("L103P") is the general partner of L103 and may be deemed to have voting, investment and dispositive power with respect to these shares. Juliet Tammenoms Bakker and the Reporting Person, a member of the board of directors of the Issuer, are the managing members of L103P, and may each be deemed to share voting, investment and dispositive power with respect to these shares. Each of L103P, Ms. Tammenoms Bakker and the Reporting Person disclaims beneficial ownership of such shares except to the extent of their respective pecuniary interests therein. |
Exhibit List: Exhibit 24 - Power of Attorney