| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Wu Xiaobin | President and COO | C/O BEONE MEDICINES I GMBH, AESCHENGRABEN 27, 21ST FLOOR, BASEL, SWITZERLAND | /s/ Qing Nian, as Attorney-in-Fact | 15 Aug 2025 | 0001739452 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ONC | American Depositary Shares | Options Exercise | $3,972,294 | +22,773 | $174.43 | 22,773 | 13 Aug 2025 | Direct | F1 | |
| transaction | ONC | American Depositary Shares | Options Exercise | $4,216,593 | +27,085 | +119% | $155.68 | 49,858 | 13 Aug 2025 | Direct | F1 |
| transaction | ONC | American Depositary Shares | Sale | $2,672,962 | -8,900 | -18% | $300.33 | 40,958 | 13 Aug 2025 | Direct | F1, F2, F3 |
| transaction | ONC | American Depositary Shares | Sale | $1,356,703 | -4,500 | -11% | $301.49 | 36,458 | 13 Aug 2025 | Direct | F1, F2, F4 |
| transaction | ONC | American Depositary Shares | Sale | $1,754,194 | -5,800 | -16% | $302.45 | 30,658 | 13 Aug 2025 | Direct | F1, F2, F5 |
| transaction | ONC | American Depositary Shares | Sale | $1,067,564 | -3,517 | -11% | $303.54 | 27,141 | 13 Aug 2025 | Direct | F1, F2, F6 |
| transaction | ONC | American Depositary Shares | Sale | $2,239,887 | -7,359 | -27% | $304.37 | 19,782 | 13 Aug 2025 | Direct | F1, F2, F7 |
| transaction | ONC | American Depositary Shares | Sale | $161,352 | -528 | -2.7% | $305.59 | 19,254 | 13 Aug 2025 | Direct | F1, F2, F8 |
| transaction | ONC | American Depositary Shares | Sale | $2,956,094 | -9,637 | -50% | $306.74 | 9,617 | 13 Aug 2025 | Direct | F1, F2, F9 |
| transaction | ONC | American Depositary Shares | Sale | $2,956,062 | -9,617 | -100% | $307.38 | 0 | 13 Aug 2025 | Direct | F1, F2, F10 |
| transaction | ONC | American Depositary Shares | Options Exercise | $4,788,094 | +30,756 | $155.68 | 30,756 | 14 Aug 2025 | Direct | F1 | |
| transaction | ONC | American Depositary Shares | Options Exercise | $1,459,895 | +9,180 | +30% | $159.03 | 39,936 | 14 Aug 2025 | Direct | F1 |
| transaction | ONC | American Depositary Shares | Sale | $120,345 | -400 | -1% | $300.86 | 39,536 | 14 Aug 2025 | Direct | F1, F2, F11 |
| transaction | ONC | American Depositary Shares | Sale | $1,751,857 | -5,800 | -15% | $302.04 | 33,736 | 14 Aug 2025 | Direct | F1, F2, F12 |
| transaction | ONC | American Depositary Shares | Sale | $2,112,586 | -6,965 | -21% | $303.31 | 26,771 | 14 Aug 2025 | Direct | F1, F2, F13 |
| transaction | ONC | American Depositary Shares | Sale | $152,097 | -500 | -1.9% | $304.19 | 26,271 | 14 Aug 2025 | Direct | F1, F2, F14 |
| transaction | ONC | American Depositary Shares | Sale | $2,603,297 | -8,522 | -32% | $305.48 | 17,749 | 14 Aug 2025 | Direct | F1, F2, F15 |
| transaction | ONC | American Depositary Shares | Sale | $3,746,189 | -12,232 | -69% | $306.26 | 5,517 | 14 Aug 2025 | Direct | F1, F2, F16 |
| transaction | ONC | American Depositary Shares | Sale | $1,511,626 | -4,917 | -89% | $307.43 | 600 | 14 Aug 2025 | Direct | F1, F2, F17 |
| transaction | ONC | American Depositary Shares | Sale | $184,819 | -600 | -100% | $308.03 | 0 | 14 Aug 2025 | Direct | F1, F2, F18 |
| holding | ONC | Ordinary Shares | 1,228,328 | 13 Aug 2025 | Direct | ||||||
| holding | ONC | American Depositary Shares | 12,365 | 13 Aug 2025 | Direct | F1 | |||||
| holding | ONC | American Depositary Shares | 4,000 | 13 Aug 2025 | By Wife | F1 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ONC | Share Option (Right to Buy) | Options Exercise | $0 | -296,049 | -100% | $0.000000 | 0 | 13 Aug 2025 | Ordinary Shares | 296,049 | $13.42 | Direct | F19, F20 |
| transaction | ONC | Share Option (Right to Buy) | Options Exercise | $0 | -352,105 | -33% | $0.000000 | 709,709 | 13 Aug 2025 | Ordinary Shares | 352,105 | $11.98 | Direct | F19, F21 |
| transaction | ONC | Share Option (Right to Buy) | Options Exercise | $0 | -399,828 | -56% | $0.000000 | 309,881 | 14 Aug 2025 | Ordinary Shares | 399,828 | $11.98 | Direct | F19, F21 |
| transaction | ONC | Share Option (Right to Buy) | Options Exercise | $0 | -119,340 | -25% | $0.000000 | 358,046 | 14 Aug 2025 | Ordinary Shares | 119,340 | $12.23 | Direct | F19, F22 |
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
| Id | Content |
|---|---|
| F1 | Each American Depositary Share represents 13 Ordinary Shares. |
| F2 | The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 13, 2024, as most recently amended on May 14, 2025. |
| F3 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $300.00 to $300.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F4 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $301.00 to $301.98, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F5 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $302.00 to $302.97, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F6 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $303.00 to $303.98, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F7 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $304.00 to $304.80, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F8 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $305.17 to $306.13, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F9 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $306.19 to $307.18, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F10 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $307.20 to $307.51, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F11 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $300.44 to $301.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F12 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $301.52 to $302.39, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F13 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $302.79 to $303.68, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F14 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $303.85 to $304.48, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F15 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $304.95 to $305.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F16 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $305.95 to $306.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F17 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $306.95 to $307.93, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F18 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $307.99 to $308.12, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F19 | The number of securities underlying each option and the exercise price therefore are represented in ordinary shares. |
| F20 | These securities vest over a four-year period as follows: 25% on June 17, 2021 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested shares are subject to accelerated vesting upon certain termination events following a change in control. |
| F21 | These securities vest over a four-year period as follows: 25% on the first anniversary of June 22, 2022, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares are subject to accelerated vesting upon certain termination events following a change in control. |
| F22 | These securities vest over a four-year period as follows: 25% on the first anniversary of June 5, 2024, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares are subject to accelerated vesting upon certain termination events. |