| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Hoffman Beth J. | Director | 120 PRESIDENTIAL WAY SUITE 330, WOBURN | /s/ Daniel Hakansson, Attorney-in-fact for Beth J. Hoffman | 16 Sep 2025 | 0001885321 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | BFRI | Employee stock option (right to buy) | Award | $0 | +20,000 | $0.000000 | 20,000 | 22 Jul 2025 | Common Stock | 20,000 | $1.00 | Direct | F1, F2 |
| Id | Content |
|---|---|
| F1 | The option vests in twelve equal monthly installments beginning on August 22, 2025. |
| F2 | Options with different terms are not included. |