Eric Westin - 25 Mar 2025 Form 3 Insider Report for BICYCLE THERAPEUTICS PLC (BCYC)

Role: Chief Medical Officer
Signature: /s/ Jason Minio, Attorney-in-Fact
Issuer symbol: BCYC
Transactions as of: 25 Mar 2025
Net transactions value: $0
Form type: 3
Filing time: 27 Mar 2025, 17:15:02 UTC
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
holding	BCYC	Ordinary Shares						2,305	25 Mar 2025	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
holding	BCYC	Employee Stock Option (right to buy)							25 Mar 2025	Ordinary Shares	6,800	$21.50	Direct	F2
holding	BCYC	Employee Stock Option (right to buy)							25 Mar 2025	Ordinary Shares	25,000	$13.39	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents a restricted share unit ("RSU") award. One-fourth (1/4) of the total number of RSUs shall vest on January 2, 2026 and the remaining RSUs shall vest in 12 equal quarterly installments thereafter.
F2	This option shall vest with respect to one-fourth (1/4) of the total number of shares underlying the option on August 5, 2025 and the remaining shares shall vest in 36 equal monthly installments thereafter.
F3	This option shall vest with respect to one-fourth (1/4) of the total number of shares underlying the option on February 3, 2026 and the remaining shares in shall vest 36 equal monthly installments thereafter.