| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| CITADEL ADVISORS LLC | 0% | -103% | $1,250 | -$367,360 | 3,732 | -100% | Kenneth Griffin | 30 Sep 2025 |
As of 31 Dec 2025, 39 institutional investors reported holding 8,179,397 shares of VYNE Therapeutics Inc. - Common Stock, par value $0.0001 per share (VYNE). This represents 44% of the company’s total 18,514,484 outstanding shares.
The largest institutional shareholders of VYNE Therapeutics Inc. - Common Stock, par value $0.0001 per share (VYNE) together control 44% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Shay Capital LLC | 8.8% | 1,624,349 | +230% | 0.15% | $942,285 |
| Anson Funds Management LP | 6.9% | 1,274,386 | 0.1% | $739,271 | |
| Nantahala Capital Management, LLC | 5.4% | 1,000,000 | 0.03% | $580,100 | |
| T3 Companies, LLC | 5.1% | 945,000 | 0% | 0.7% | $548,195 |
| ACADIAN ASSET MANAGEMENT LLC | 3.4% | 638,492 | +43% | 0% | $370,000 |
| KVP Capital Advisors, LP | 2.7% | 500,551 | 0% | 0.3% | $290,370 |
| VANGUARD GROUP INC | 1.7% | 314,545 | +65% | 0% | $182,436 |
| Ikarian Capital, LLC | 1.4% | 264,912 | -8.7% | 0.02% | $153,675 |
| ADAR1 Capital Management, LLC | 1.4% | 253,791 | 0.01% | $147,224 | |
| GEODE CAPITAL MANAGEMENT, LLC | 1.2% | 225,152 | +64% | 0% | $130,614 |
| TWO SIGMA INVESTMENTS, LP | 1.2% | 220,000 | -0.36% | 0% | $127,622 |
| TWO SIGMA ADVISERS, LP | 0.88% | 163,100 | +188% | 0% | $94,614 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.54% | 100,341 | +74% | 0% | $58,207 |
| Rangeley Capital, LLC | 0.54% | 100,000 | +100% | 0.05% | $58,010 |
| BOOTHBAY FUND MANAGEMENT, LLC | 0.44% | 81,371 | -24% | 0% | $47,203 |
| XTX Topco Ltd | 0.43% | 79,040 | 0% | $45,851 | |
| JANE STREET GROUP, LLC | 0.39% | 72,356 | -51% | 0% | $41,974 |
| UBS Group AG | 0.34% | 62,761 | +1026% | 0% | $36,401 |
| GSA CAPITAL PARTNERS LLP | 0.29% | 53,961 | +50% | 0% | $31,000 |
| BlackRock, Inc. | 0.24% | 44,404 | 0% | 0% | $25,759 |
| CITADEL ADVISORS LLC | 0.16% | 30,526 | 0% | $17,708 | |
| Virtu Financial LLC | 0.14% | 25,327 | 0% | $15,000 | |
| FNY Investment Advisers, LLC | 0.14% | 25,000 | 0% | $14,000 | |
| NORTHERN TRUST CORP | 0.12% | 23,110 | 0% | 0% | $13,406 |
| COMMONWEALTH EQUITY SERVICES, LLC | 0.1% | 18,298 | 0% | 0% | $10,610 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 8,179,397 | $4,743,526 | +$1,869,192 | $0.58 | 39 |
| 2025 Q3 | 3,924,005 | $1,315,944 | -$9,032,746 | $0.34 | 31 |
| 2025 Q2 | 8,048,768 | $13,279,291 | +$1,503,898 | $1.65 | 44 |
| 2025 Q1 | 7,109,939 | $11,401,092 | -$2,382,241 | $1.58 | 36 |
| 2024 Q4 | 7,028,274 | $23,320,995 | +$606,162 | $3.35 | 34 |
| 2024 Q3 | 7,312,555 | $14,256,902 | -$1,226,342 | $1.88 | 31 |
| 2024 Q2 | 7,942,286 | $16,030,293 | +$243,077 | $1.97 | 30 |
| 2024 Q1 | 6,405,086 | $19,663,149 | +$378,435 | $3.07 | 29 |
| 2023 Q4 | 7,863,834 | $18,322,345 | +$17,207,859 | $2.33 | 32 |
| 2023 Q3 | 360,099 | $1,445,870 | -$33,734 | $4.04 | 20 |
| 2023 Q2 | 375,960 | $1,532,386 | +$198,131 | $4.10 | 19 |
| 2023 Q1 | 335,259 | $1,031,948 | +$1,031,948 | $3.08 | 19 |