| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Farallon Capital Partners, L.P. | 7.5% | -5% | $1,499,170,464 | +$137,025,822 | 14,596,149 | +10% | Dapice Joshua J. | 31 Dec 2025 |
| JANUS HENDERSON GROUP PLC | 6.1% | +6.7% | $530,327,722 | +$35,740,771 | 11,356,054 | +7.2% | JANUS HENDERSON GROUP PLC | 30 Sep 2025 |
| BAKER BROS. ADVISORS LP | 4.9% | -2% | $971,159,717 | +$9,283,443 | 9,455,357 | +0.97% | Baker Bros. Advisors LP | 31 Dec 2025 |
| FMR LLC | 5% | $439,058,769 | 9,401,687 | FMR LLC | 30 Sep 2025 | |||
| BlackRock, Inc. | 4.5% | $309,009,603 | 8,399,214 | BlackRock, Inc. | 30 Jun 2025 | |||
| WELLINGTON MANAGEMENT GROUP LLP | 3.6% | -32% | $717,700,402 | -$336,077,288 | 6,987,639 | -32% | Wellington Management Group LLP | 31 Dec 2025 |
As of 31 Dec 2025, 383 institutional investors reported holding 199,280,276 shares of Revolution Medicines, Inc. - Common Stock, par value $0.0001 per share (RVMD). This represents 103% of the company’s total 192,966,469 outstanding shares.
The largest institutional shareholders of Revolution Medicines, Inc. - Common Stock, par value $0.0001 per share (RVMD) together control 73% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 8.7% | 16,719,886 | +6.7% | 0.02% | $1,331,738,920 |
| FARALLON CAPITAL MANAGEMENT LLC | 7.6% | 14,582,796 | -0.29% | 6.7% | $1,161,519,701 |
| JANUS HENDERSON GROUP PLC | 6.4% | 12,303,502 | +8.3% | 0.44% | $980,035,989 |
| BAKER BROS. ADVISORS LP | 4.9% | 9,455,357 | 0% | 4.4% | $753,119,185 |
| BlackRock, Inc. | 4.6% | 8,926,656 | +7.2% | 0.01% | $711,008,150 |
| FMR LLC | 4.5% | 8,587,981 | -8.7% | 0.03% | $684,032,699 |
| Nextech Invest, Ltd. | 3.9% | 7,601,087 | 0% | 59% | $605,426,580 |
| WELLINGTON MANAGEMENT GROUP LLP | 3.6% | 6,987,639 | -29% | 0.1% | $556,565,446 |
| Paradigm Biocapital Advisors LP | 3.4% | 6,644,403 | +6.8% | 14% | $529,226,699 |
| Bellevue Group AG | 2.6% | 5,005,719 | -10% | 7.6% | $398,705,518 |
| STATE STREET CORP | 2.1% | 4,109,290 | -22% | 0.01% | $327,304,949 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.8% | 3,404,717 | -12% | 0.03% | $271,186,000 |
| BVF INC/IL | 1.7% | 3,356,782 | -16% | 9% | $267,367,686 |
| Alphabet Inc. | 1.7% | 3,345,102 | -19% | 10% | $266,437,374 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.6% | 3,161,963 | +0.52% | 0.02% | $251,911,578 |
| UBS Group AG | 1.6% | 3,087,937 | +184% | 0.05% | $245,954,181 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1.5% | 2,894,613 | -21% | 3% | $230,555,925 |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 1.5% | 2,845,013 | +13% | 0.94% | $226,605,319 |
| GENERAL ATLANTIC, L.P. | 1.5% | 2,812,928 | +14% | 7.8% | $224,049,715 |
| Casdin Capital, LLC | 1.3% | 2,577,333 | -2.6% | 13% | $205,284,573 |
| Woodline Partners LP | 1.3% | 2,500,895 | -14% | 0.77% | $199,196,287 |
| GOLDMAN SACHS GROUP INC | 1.3% | 2,491,274 | +238% | 0.03% | $198,429,974 |
| NORGES BANK | 1.3% | 2,455,347 | 0.02% | $195,568,389 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.1% | 2,205,555 | +197% | 0.27% | $175,672,456 |
| T. Rowe Price Investment Management, Inc. | 1.1% | 2,200,376 | -54% | 0.11% | $175,260,000 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 199,280,276 | $15,873,982,580 | +$504,539,283 | $79.65 | 383 |
| 2025 Q3 | 191,767,706 | $8,955,119,353 | +$87,454,891 | $46.70 | 318 |
| 2025 Q2 | 190,726,235 | $7,017,009,498 | -$4,134,347 | $36.79 | 305 |
| 2025 Q1 | 191,051,347 | $6,776,444,446 | -$111,943,197 | $35.36 | 281 |
| 2024 Q4 | 193,048,484 | $8,445,124,761 | +$672,301,180 | $43.74 | 278 |
| 2024 Q3 | 170,577,261 | $7,735,337,873 | +$69,484,732 | $45.35 | 252 |
| 2024 Q2 | 168,410,110 | $6,536,274,916 | +$309,463,084 | $38.81 | 221 |
| 2024 Q1 | 160,549,965 | $5,174,502,235 | +$41,971,613 | $32.23 | 207 |
| 2023 Q4 | 159,991,814 | $4,588,662,174 | +$1,173,667,984 | $28.68 | 183 |
| 2023 Q3 | 112,410,338 | $3,111,480,815 | +$13,449,543 | $27.68 | 165 |
| 2023 Q2 | 111,960,439 | $2,994,417,481 | +$107,072,959 | $26.75 | 138 |
| 2023 Q1 | 108,245,336 | $2,343,498,970 | +$420,665,649 | $21.66 | 149 |
| 2022 Q4 | 88,251,337 | $2,102,174,977 | +$32,658,345 | $23.82 | 133 |
| 2022 Q3 | 88,392,782 | $1,743,047,001 | +$233,806,685 | $19.72 | 133 |
| 2022 Q2 | 76,461,750 | $1,490,187,152 | +$40,971,035 | $19.49 | 125 |
| 2022 Q1 | 73,955,592 | $1,885,584,241 | +$15,751,102 | $25.51 | 122 |
| 2021 Q4 | 73,332,089 | $1,845,795,329 | -$50,104,402 | $25.17 | 113 |
| 2021 Q3 | 68,952,735 | $1,896,915,710 | +$49,809,012 | $27.51 | 109 |
| 2021 Q2 | 70,364,140 | $2,233,248,707 | +$91,598,352 | $31.74 | 127 |
| 2021 Q1 | 66,456,882 | $3,048,913,145 | +$424,322,383 | $45.88 | 124 |
| 2020 Q4 | 57,426,011 | $2,273,517,142 | +$133,648,027 | $39.59 | 118 |
| 2020 Q3 | 56,953,834 | $1,981,075,717 | +$339,721,674 | $34.80 | 90 |
| 2020 Q2 | 46,886,789 | $1,478,128,925 | +$22,763,370 | $31.57 | 73 |
| 2020 Q1 | 46,881,176 | $1,025,119,285 | +$1,024,845,284 | $21.91 | 72 |