| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| SABBY MANAGEMENT, LLC | 9.9% | $628,817 | 175,158 | SABBY MANAGEMENT, LLC | 31 Dec 2025 |
As of 31 Dec 2025, 22 institutional investors reported holding 242,614 shares of Lyra Therapeutics, Inc. - Common Stock (LYRA). This represents 14% of the company’s total 1,769,273 outstanding shares.
The largest institutional shareholders of Lyra Therapeutics, Inc. - Common Stock (LYRA) together control 14% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| SABBY MANAGEMENT, LLC | 9.9% | 175,158 | +37% | 4.5% | $539,487 |
| Ikarian Capital, LLC | 1.2% | 21,161 | 0% | 0.01% | $65,176 |
| DRW Securities, LLC | 0.95% | 16,812 | 0% | $51,780 | |
| GEODE CAPITAL MANAGEMENT, LLC | 0.69% | 12,249 | +11% | 0% | $37,733 |
| Artia Global Partners LP | 0.49% | 8,756 | 0% | $26,968 | |
| BlackRock, Inc. | 0.14% | 2,394 | +42% | 0% | $7,373 |
| Tower Research Capital LLC (TRC) | 0.12% | 2,191 | +310% | 0% | $6,748 |
| ROYAL BANK OF CANADA | 0.11% | 1,928 | +46% | 0% | $6,000 |
| UBS Group AG | 0.04% | 675 | -83% | 0% | $2,079 |
| EverSource Wealth Advisors, LLC | 0.02% | 338 | -2% | 0% | $1,041 |
| MORGAN STANLEY | 0.02% | 334 | -74% | 0% | $1,029 |
| JONES FINANCIAL COMPANIES LLLP | 0.01% | 210 | 0% | 0% | $647 |
| BANK OF AMERICA CORP /DE/ | 0.01% | 201 | +1017% | 0% | $619 |
| SBI Securities Co., Ltd. | 0% | 80 | 0% | 0% | $246 |
| JPMORGAN CHASE & CO | 0% | 27 | 0% | 0% | $83 |
| COMERICA BANK | 0% | 23 | 0% | 0% | $71 |
| OSAIC HOLDINGS, INC. | 0% | 22 | 0% | 0% | $67 |
| Wilmington Savings Fund Society, FSB | 0% | 20 | 0% | 0% | $62 |
| BNP PARIBAS FINANCIAL MARKETS | 0% | 16 | 0% | 0% | $49 |
| Global Retirement Partners, LLC | 0% | 15 | 0% | $46 | |
| CITIGROUP INC | 0% | 3 | -100% | 0% | $9 |
| IFP Advisors, Inc | 0% | 1 | -50% | 0% | $3 |
| CITADEL ADVISORS LLC | 0% | 0 | -100% | $0 | |
| Signature Resources Capital Management, LLC | 0% | 0 | -100% | $0 | |
| VANGUARD GROUP INC | 0% | 0 | -100% | $0 |