IO Biotech, Inc. - Common (IOBT) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2021 to Q4 2025

Type / Class
Equity / Common
Symbol
IOBT on Nasdaq
Shares outstanding
72,119,556
Price per share
$0.32
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
7,848,183
Total reported value
$4,778,900
% of total 13F portfolios
0%
Share change
-2,047,692
Value change
-$1,143,305
Number of holders
22
Price from insider filings
$0.32
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of IO Biotech, Inc. - Common (IOBT) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
HBM Healthcare Investments (Cayman) Ltd. 8.2% $5,412,970 5,523,439 HBM Healthcare Investments (Cayman) Ltd. 31 Dec 2023
Chernett Jorey 6.3% +20% $2,317,201 +$543,849 4,543,532 +31% Chernett Jorey 31 Dec 2025
Point72 Asset Management, L.P. 5.6% $2,452,108 4,027,112 Point72 Asset Management, L.P. 05 Feb 2026
Samsara BioCapital, L.P. 3.8% $2,578,946 2,631,578 Samsara BioCapital, L.P. 31 Dec 2024
Novo Holdings A/S 3.3% -57% $1,827,160 -$1,859,215 2,469,135 -50% Novo Holdings A/S 21 Jan 2026

As of 31 Dec 2025, 22 institutional investors reported holding 7,848,183 shares of IO Biotech, Inc. - Common (IOBT). This represents 11% of the company’s total 72,119,556 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of IO Biotech, Inc. - Common (IOBT) together control 11% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
NOVO HOLDINGS A/S 3.5% 2,512,453 0% 0.12% $1,529,833
Ikarian Capital, LLC 1.9% 1,386,565 -9.1% 0.11% $844,279
BANK OF AMERICA CORP /DE/ 1.1% 799,953 0% 0% $486,371
MORGAN STANLEY 0.75% 539,182 -19% 0% $328,308
Beacon Pointe Advisors, LLC 0.7% 506,000 0% $308,104
BOOTHBAY FUND MANAGEMENT, LLC 0.63% 451,852 -24% 0.01% $275,133
Dauntless Investment Group, LLC 0.63% 451,641 1.1% $275,004
MARSHALL WACE, LLP 0.6% 429,338 -59% 0% $261,897
RENAISSANCE TECHNOLOGIES LLC 0.29% 207,601 -62% 0% $126,408
MILLENNIUM MANAGEMENT LLC 0.19% 138,716 -90% 0% $84,464
CITIGROUP INC 0.15% 111,447 +8526% 0% $67,860
BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.1% 75,000 0% 0% $45,668
TWO SIGMA SECURITIES, LLC 0.06% 44,757 0% $27,253
UBS Group AG 0.06% 43,578 +521% 0% $26,539
GEODE CAPITAL MANAGEMENT, LLC 0.05% 33,307 0% 0% $20,280
Hilton Capital Management, LLC 0.04% 25,510 0% 0% $15,533
ADAR1 Capital Management, LLC 0.03% 24,964 0% $15,201
PKS Advisory Services, LLC 0.03% 20,000 +2.6% 0% $12,178
Virtu Financial LLC 0.03% 19,078 -51% 0% $12,000
XTX Topco Ltd 0.02% 15,864 -91% 0% $9,660
Scientech Research LLC 0.02% 11,255 0% $6,853
SBI Securities Co., Ltd. 0% 122 0% 0% $74
Quadrature Capital Ltd 0% 0 -100% $0
GOLDMAN SACHS GROUP INC 0% 0 -100% $0
NewEdge Advisors, LLC 0% 0 -100% $0

Institutional Holders of IO Biotech, Inc. - Common (IOBT) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 7,848,183 $4,778,900 -$1,143,305 $0.61 22
2025 Q3 9,895,875 $3,589,663 -$13,417,589 $0.36 21
2025 Q2 18,182,707 $25,273,480 -$1,285,024 $1.39 26
2025 Q1 19,066,617 $20,781,978 -$660,538 $1.09 21
2024 Q4 19,692,862 $18,114,763 -$4,833,042 $0.92 26
2024 Q3 23,591,882 $24,769,965 -$2,959,503 $1.05 19
2024 Q2 26,183,049 $30,634,167 -$1,443,320 $1.17 19
2024 Q1 27,341,910 $47,354,293 -$3,558,302 $1.73 17
2023 Q4 29,400,721 $55,273,224 +$999,356 $1.88 18
2023 Q3 29,668,665 $41,702,613 +$24,426,263 $1.41 19
2023 Q2 12,246,779 $23,953,554 -$3,111,706 $1.96 15
2023 Q1 13,917,553 $26,081,803 -$1,175,062 $1.88 17
2022 Q4 14,281,285 $32,846,954 -$2,578,155 $2.30 17
2022 Q3 15,335,530 $41,559,000 -$326,875 $2.71 20
2022 Q2 15,453,557 $72,167,000 +$2,681,635 $4.67 18
2022 Q1 14,858,852 $76,863,500 -$1,060,884 $5.30 19
2021 Q4 12,982,583 $82,349,000 +$82,349,000 $6.40 19