IONIS PHARMACEUTICALS INC financial data

Symbol
IONS on Nasdaq
Location
Carlsbad, CA
Fiscal year end
31 December
Latest financial report
10-K - Q4 2025 - 26 Feb 2026

Key Ratios

Label TTM Value / Value Unit Change %
Current Ratio 371% % -54%
Quick Ratio 1.4% % -82%
Debt-to-equity 458% % -15%
Return On Assets -12% % 22%

Shares

Label TTM Value / Value Unit Change %
Entity Common Stock, Shares Outstanding 165,192,011 shares 3.8%
Common Stock, Shares, Outstanding 163,304,875 shares 3.4%
Entity Public Float $5,275,488,712 USD -8.1%
Common Stock, Value, Issued $163,000 USD 3.2%
Weighted Average Number of Shares Outstanding, Basic 160,010,000 shares 7%
Weighted Average Number of Shares Outstanding, Diluted 160,010,000 shares 7%

Income Statement

Label TTM Value / Value Unit Change %
Revenues $203,330,000 USD -10%
Revenue from Contract with Customer, Excluding Assessed Tax $943,711,000 USD 34%
Costs and Expenses $1,325,395,000 USD 12%
Operating Income (Loss) $381,685,000 USD 20%
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest $379,601,000 USD 17%
Income Tax Expense (Benefit) $1,786,000 USD
Net Income (Loss) Attributable to Parent $381,387,000 USD 16%
Earnings Per Share, Basic -2.36 USD/shares 22%
Earnings Per Share, Diluted -2.44 USD/shares 20%

Balance Sheet

Label TTM Value / Value Unit Change %
Cash and Cash Equivalents, at Carrying Value $372,260,000 USD 54%
Inventory, Net $10,048,000 USD -20%
Other Assets, Current $237,092,000 USD 8.8%
Assets, Current $2,990,635,000 USD 14%
Property, Plant and Equipment, Net $123,048,000 USD 31%
Operating Lease, Right-of-Use Asset $238,549,000 USD 47%
Other Assets, Noncurrent $171,604,000 USD 35%
Assets $3,523,836,000 USD 17%
Accounts Payable, Current $28,082,000 USD -35%
Employee-related Liabilities, Current $116,236,000 USD 67%
Accrued Liabilities, Current $106,089,000 USD -2.2%
Contract with Customer, Liability, Current $73,761,000 USD -6.6%
Liabilities, Current $781,567,000 USD 153%
Contract with Customer, Liability, Noncurrent $92,001,000 USD -41%
Operating Lease, Liability, Noncurrent $262,383,000 USD 62%
Other Liabilities, Noncurrent $28,785,000 USD -31%
Liabilities $3,034,747,000 USD 26%
Accumulated Other Comprehensive Income (Loss), Net of Tax $25,281,000 USD 18%
Retained Earnings (Accumulated Deficit) $2,631,195,000 USD -17%
Stockholders' Equity Attributable to Parent $489,089,000 USD -17%
Liabilities and Equity $3,523,836,000 USD 17%

Popular Metrics

Label TTM Value / Value Unit Change %
Net Cash Provided by (Used in) Operating Activities $150,775,000 USD -0.56%
Net Cash Provided by (Used in) Financing Activities $2,199,000 USD -91%
Net Cash Provided by (Used in) Investing Activities $170,459,000 USD 124%
Common Stock, Shares Authorized 300,000,000 shares 0%
Common Stock, Shares, Issued 163,304,875 shares 3.4%
Common Stock, Par or Stated Value Per Share 0.001 USD/shares 0%
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect $22,115,000 USD
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents $372,260,000 USD 54%
Interest Paid, Excluding Capitalized Interest, Operating Activities $92,000 USD -3.2%
Deferred Tax Assets, Valuation Allowance $1,236,935,000 USD 9.5%
Deferred Tax Assets, Gross $1,310,891,000 USD 12%
Operating Lease, Liability $271,892,000 USD 59%
Depreciation $2,228,000 USD -13%
Payments to Acquire Property, Plant, and Equipment $12,577,000 USD 180%
Comprehensive Income (Loss), Net of Tax, Attributable to Parent $375,857,000 USD 17%
Lessee, Operating Lease, Liability, to be Paid $484,816,000 USD 86%
Operating Lease, Liability, Current $9,509,000 USD 4.9%
Lessee, Operating Lease, Liability, to be Paid, Year Two $36,564,000 USD 74%
Lessee, Operating Lease, Liability, to be Paid, Year One $35,531,000 USD 70%
Operating Lease, Weighted Average Discount Rate, Percent 0.07 pure 1.4%
Lessee, Operating Lease, Liability, Undiscounted Excess Amount $212,924,000 USD 138%
Lessee, Operating Lease, Liability, to be Paid, Year Three $36,877,000 USD 75%
Deferred Tax Assets, Operating Loss Carryforwards $290,851,000 USD 203%
Unrecognized Tax Benefits $53,962,000 USD 31%
Lessee, Operating Lease, Liability, to be Paid, Year Four $34,948,000 USD 67%
Amortization of Intangible Assets $582,000 USD -8.9%
Share-based Payment Arrangement, Expense $133,874,000 USD 2.8%
Interest Expense $17,262,000 USD 1.6%